Sesquiterpenes and Other Constituents from Dendranthema zawadskii var. latilobum
スポンサーリンク
概要
- 論文の詳細を見る
Six new germacranolides, zawadskinolides A—F (1—6), and a new eudesmane glucoside, chrysantiloboside (7) were isolated from the aerial parts of Dendranthema zawadskii var. latilobum, along with thirteen known constituents. Their structures were elucidated by means of spectroscopic evidence. Bioassay showed that flavonoids such as apigenin (9), (−)-eriodictyol (10) and nepetin (12), as well as the sesquiterpene lactone, zawadskinolide F (6), inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells with IC50 values of 66.15, 132.55, 35.44, and 91.32 μM, respectively.
- 公益社団法人 日本薬学会の論文
著者
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Kim Yeong
Natural Products Res. Inst. Coll. Of Pharmacy Seoul National Univ.
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Lee Sanghyun
Department Of Applied Plant Science Chung-ang University
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Kang Sam
Natural Product Research Institute Seoul National University
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Kim Ju
Natural Products Res. Inst. And Coll. Of Pharmacy Seoul National Univ.
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Lee So
Natural Products Research Institute and College of Pharmacy, Seoul National University
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Choi Ran
Natural Products Research Institute and College of Pharmacy, Seoul National University
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Shin Hyun
Natural Products Research Institute and College of Pharmacy, Seoul National University
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Chung Ha
Department of Foods and Nutrition, College of Natural Sciences, Duksung Women’s University
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Kim Ju
Natural Products Research Institute and College of Pharmacy, Seoul National University
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Chung Ha
Department of Foods and Nutrition, College of Natural Sciences, Duksung Women's University
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Kim Yeong
Natural Products Research Institute and College of Pharmacy, Seoul National University
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Lee Sanghyun
Department of Integrative Plant Science, College of Natural Science, Chung-Ang University
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