過栄養性脂肪肝における血清コリンエステラーゼ活性-肥満のその活性に及ぼす影響と慢性肝炎との鑑別における有用性

概要

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Serum cholinesterase activity was found to be increased in non-obese as well as obese patients with non-alcoholic fatty liver, whereas obese subjects with no evidence of hepatic steatosis showed values slightly higher than those in controls. The activity was increased in 79% of patients with non-alcoholic fatty liver, in 23% of those with chronic persistent hepatitis, in 8% of those with chronic active hepatitis and in none of the patients with liver cirrhosis. By setting the upper limit at an above normal level, 42% of the patients with non-alcoholic fatty liver could be differentiated from patients with chronic hepatitis. When obese patients with fatty liver were followed with a low-caloric diet, cholinesterase activity was decreased reflecting improvement of hepatic steatosis.
財団法人日本消化器病学会の論文