熱酸化重合油に対するトコール誘導体の補充効果の比較 (変敗油の毒性-11,12-)

概要

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In the previous papers, the authors reported that tocopherol reduced the toxicity of thermally oxidized oils. In order to compare the biological activity among tocol derivatives, rats were fed with a diet containing thermally oxidized soybean oil with tocol derivatives (dl-α-, δ-and mixed-tocopherol). The results indicated that the rats fed with thermally oxidized oil showed growth deprssion and ruffed hair, whereas better growth was observed when the rats were fed with the same oil with tocopherols, and the best growth was recognized on α-tocopherol. The liver weights and the lipid contents of liver fed with thermally oxidized oil were higher than those of the rats fed with fresh oil. However, both of them were decreased by tocol derivatives. Percentage of linoleate and linolenate in liver lipids fed with thermally oxidized oil with tocopherols was higher than that of tocopherol-free group, and the greatest antioxidative activity was recognized with mixed-tocopherol, followed by δ-tocopherol, α-tocopherol in the order.
日本油化学会の論文