Prevention of Melanin Formation by Yeast Cerebroside in B16 Mouse Melanoma Cells
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概要
- 論文の詳細を見る
The effects of plant and yeast cerebrosides on melanin formation were examined in B16 mouse melanoma cells. Addition of yeast cerebroside significantly reduced melanin content to the same level as that of arbutin in control cells, although there was no suppression by plant cerebrosides and bovine brain cerebroside up-regulated melanin formation. None of the bovine brain cerebrosides examined had any effect on tyrosinase activity, but yeast cerebroside reduced the contents of tyrosinase . The results of the present study clearly showed that melanin formation is regulated by several different cerebrosides via tyrosinase. In addition, the findings presented here suggest that cerebrosides containing a 9-methyl type sphingoid base, such as yeast cerebroside, may be useful as skincare products for suppressing melanin formation.
- 日本油化学会の論文
著者
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Ohnishi Masao
Department Of Agricultural And Life Science Obihiro University Of Agriculture And Veterinary Medicin
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Aida Kazuhiko
Central Laboratory Nippon Flour Mills Co. Ltd
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Aida Kazuhiko
Nippon Flour Mills Co. Ltd. Central Laboratory
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Sugawara Tatsuya
Division Of Applied Biosciences Graduate School Of Agriculture Kyoto University
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Kinoshita Mikio
Department Of Agricultural And Life Sciences Obihiro University Of Agriculture And Veterinary Medici
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Hori Naofumi
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medici
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Aida Kazuhiko
Central Laboratory Nippon Flour Mill Co Ltd
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KINOSHITA Mikio
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine
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Sugawara Tatsuya
Division of Applied Biosciences, Graduated School of Agriculture, Kyoto University
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