Truncated Sla1 Induces Haploid Meiosis through the Path1-Mei2 System in Fission Yeast
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概要
- 論文の詳細を見る
We previously reported that expression of Sla1ΔC, a truncated form of Sla1, induces ectopic meiosis in heterothallic fission yeast and this was possibly due to the inhibition of Pat1 kinase by Sla1ΔC. Here we found mei2 mRNA and the Mei2 protein accumulated and stability of the Mei2 protein increased when Sla1ΔC was expressed. The former two results are considered to be the consequence of de-repression of Ste11, which is the transcription factor of mei2 and negatively regulated by Pat1 kinase. The latter result reflects the consequence of deregulation of Mei2 by Pat1 kinase. In addition, Ste11 accumulated in the nucleus when Sla1ΔC was expressed. All these data consistently support the idea that the action of Sla1ΔC is to inactivate Pat1 kinase.
- 社団法人 日本農芸化学会の論文
- 2004-01-23
著者
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Tanaka K
Institute Of Molecular And Cellular Biosciences The University Of Tokyo
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KAWAMUKAI Makoto
Department of Applied Bioscience and Biotechnology, Faculty of Life and Environmental Science
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MATSUDA Hideyuki
Department of Applied Bioscience and Biotechnology, Faculty of Life and Environmental Science
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Tanaka Katsunori
Department of Applied Bioscience and Biotechnology, Faculty of Life and Environmental Science, Shima
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Tanaka K
Tottori Univ. Tottori
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Tanaka Kiyoshi
Coll. Environ. Health Azabu Univ.
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TANABE Kaori
Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane Uni
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Kawamukai Makoto
Department Of Applied Bioscience And Biotechnology Faculty Of Life And Environmental Science Shimane
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Morita K
Department Of Applied Bioscience And Biotechnology Faculty Of Life And Environmental Science Shimane
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Kawamukai M
Department Of Applied Bioscience And Biotechnology Faculty Of Life And Environmental Science Shimane
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Matsuda H
Department Of Applied Bioscience And Biotechnology Faculty Of Life And Environmental Science Shimane
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Matsuda Hideyuki
Department Of Applied Bioscience And Biotechnology Faculty Of Life And Environmental Science Shimane
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Kawamukai Makoto
Department Of Life Science And Biotechnology Faculty Of Life And Environmental Science Shimane Unive
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Kikuchi Takao
Coll. Environ. Health Azabu Univ.
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Tanaka Keiko
Department Of Food Science And Technology Faculty Of Agriculture Kyoto University
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Kawamukai Makoto
Department Of Life Science And Biotechnology Faculty Of Life And Environmental Science Shimane Unive
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Koyanagi Takashi
Research Institute For Bioresources And Biotechnology Ishikawa Prefectural University
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Tanaka Kyoko
Graduate School of Life and Environmental Sciences, Kyoto Prefectural University
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