Production of equol from daidzein by gram-positive rod-shaped bacterium isolated from rat intestine.
スポンサーリンク
概要
- 論文の詳細を見る
Isoflavones (mainly daidzein and genistin) belong to the flavonoid group of compounds and are classified as phytoestrogens. In the intestine, daidzin is converted to daidzein by β-glucosidase, and then daidzein is converted to O-desmethylangolensin (O-DMA) or equol via dihydrodaidzein by enzymes of intestinal bacteria. We isolated, for the first time, an anaerobic gram-positive rod-shaped strain capable of producing equol from daidzein. Its 16S rDNA gene sequence (1428 bp) showed 99% similarity with that of the human intestinal bacterium SNU-Julong 732 (AY310748) and 93% similarity with that of Eggerthella lenta ATCC 25559T (AF292375). This strain converted daidzein to equol via dihydrodaidzein in an equol-assay medium anaerobically. The addition of butyric acid and arginine increased the conversion ratio of daidzein to equol 4.7- and 4.5-fold, respectively.
- 社団法人日本生物工学会の論文
- 2006-09-25
著者
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Sone Teruo
Laboratory Of Applied Microbiology Graduate School Of Agriculture Hokkaido University
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Sone Teruo
北海道大学 農学研究院応用生命科学部門
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Sone Teruo
Laboratory Of Applied Microbiology Research Group Of Molecular Bioscience Division Of Applied Biosci
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Tanaka Michiko
Laboratory Of Applied Microbiology Graduate School Of Agriculture Hokkaido University
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Tanaka Michiko
Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
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Sone Teruo
Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
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ASANO Kozo
Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
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Minamida Kimiko
Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
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Abe Ayumi
Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
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Tomita Fusao
Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
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Kara Hiroshi
Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
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冨田 房男
北海道大学農学部
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冨田 房男
Hokkaido Study Center The University Of Air
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Abe Ayumi
Department Of Bioscience And Chemistry Graduate School Of Agriculture Hokkaido University
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Sone T
Laboratory Of Applied Microbiology Graduate School Of Agriculture Hokkaido University
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Sone Teruo
Laboratory Of Applied Microbiology Department Of Bioscience And Chemistry Faculty Of Agriculture Hok
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Asano Kozo
Lab. Of Applied Microbiology Graduate School Of Agriculture Hokkaido Univ. Kita-9 Nishi-9 Sapporo 06
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Asano K
Foods And Liquors Research Laboratories Kyowa Hakko Kogyo Co. Ltd.
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Asano Kozo
北海道大学農学部応用生命科学専攻
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Asano Kozo
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
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Tanaka M
Laboratory Of Applied Microbiology Graduate School Of Agriculture Hokkaido University
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Tomita Fusao
Hokkaido University:hokkaido Study Center University Of The Air
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Tomita Fusao
Laboratory Of Applied Microbiology
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Tomita Fusao
Department Of Agricultural Chemistry Faculty Of Agriculture Hokkaido University
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Tomita Fusao
Department Of Agricultural Biochemistry Faculty Of Agriculture Hokkaido University
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Tomita Fusao
Laboratory Of Applied Microbiology Department Of Bioscience And Chemistry Faculty Of Agriculture Hok
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Kara Hiroshi
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
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Shiomi Takuya
Fancl Res. Inst. Fancl Corp.
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Tomita Fusao
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
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Takebayashi M
Laboratory Of Applied Microbiology Graduate School Of Agriculture Hokkaido University
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Minamida Kimiko
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
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Abe Ayumi
Research Faculty Of Agriculture Hokkaido University
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Hara Hiroshi
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
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Tanaka Michiko
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
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Sone Teruo
Laboratory of Applied Microbiology, Graduate Faculty of Agriculture, Hokkaido University
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Tanaka Michiko
Laboratory of Applied Microbiology, Graduate Faculty of Agriculture, Hokkaido University
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Abe Ayumi
Laboratory of Applied Microbiology, Graduate Faculty of Agriculture, Hokkaido University
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