潰瘍性大腸炎の臨床的検討

概要

論文の詳細を見る
Twenty seven patients with ulcerative colitis had been found and observed in our hospital since July 1971 to March 1976. Annual number of newly diagnosed patients had been no definite variation in each year. The peak age incidence was in the third decade for either sex. Main symptoms were diarrhea and bloody stool. In active stage, endoscopic finding revealed contact bleeding and granularity, and barium enema examination showed loss of haustrations, spiculation and coarse mucosal pattern rather frequently. Clinical type of the twenty six cases was relapsing-remitting one, and the rest was chronic continuous type. In twenty five cases, anatomical distributions of the lesion had been confirmed by barium enema and/or endoscopy, there were 7 cases with proctosigmoiditis, 8 left-sided colitis, 9 total colitis and one of segmental colitis. Biopsy specimens performed periodically revealed the characteristic features of the ulcerative colitis such as small round cell infiltration in lamina propria and goblet cell depletion, as well as crypt abscess. All the patients had been treated medically. So far, none of them was treated surgically or died.
北里大学の論文
1977-02-28