Involvement of Oxidative Stress Induction in Na^+ Toxicity and Its Relation to the Inhibition of a Ca^<2+>-Dependent but Calcineurin-Independent Mechanism in Saccharomyces cerevisiae(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
スポンサーリンク
概要
- 論文の詳細を見る
Uridine 5'-hexadecylphosphate (UMPC16) inhibited the growth of Saccharomyces cerevisiae under a hypersaline stress condition with Na^+ more strongly than the calcineurin inhibitor cyclosporine A (CsA). Additional Ca^<2+> supplementation similarly suppressed the inhibitory activities of UMPC16 and CsA on yeast cell growth in a medium with Na^+. UMPC16, but not CsA, accelerated mitochondrial reactive oxygen species (ROS) generation in combination with Na^+, suggesting its inhibition of a Ca^<2+>-dependent but calcineurin-independent mechanism for protection against Na^+ toxicity.
- 社団法人日本生物工学会の論文
- 2006-01-25
著者
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Tano Tatsuo
Department Of Bioresources Chemistry Faculty Of Agriculture Okayama University
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Fukamachi K
Department Of Molecular Toxicology Nagoya City University Graduate School Of Medical Sciences
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Tanaka T
Graduate School Of Science Osaka City University
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Fujita K
Graduate School Of Science Osaka City University
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Fujita K
Tohoku Univ. Sendai Jpn
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Tanaka Toshio
Department Of Respiratory Medicine Allergy And Rheumatic Disease Osaka University Graduate School Of
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USUKI Yoshinosuke
Department of Material Science, Graduate School of Science, Osaka City University
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Nishio Kyoichi
Department of Biology and Geosciences, Graduate School of Science, Osaka City University
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Fujita Kenichi
Department of Biology and Geosciences, Graduate School of Science, Osaka City University
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Fujita Ken-ichi
Graduate School Of Science Osaka City University
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Nishio Kyoichi
Department Of Biology And Geosciences Graduate School Of Science Osaka City University
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Usuki Yoshinosuke
Graduate School Of Science Osaka City University
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Fujita Ken-ichi
Department Of Biology And Geosciences Graduate School Of Science Osaka City University
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Fujita Kenichi
Department Of Biochemistry And Molecular Biology Nihon University School Of Dentistry At Matsudo
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Usuki Y
Department Of Materials Science Graduate School Of Science Osaka City University
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Usuki Yoshinosuke
Department Of Chemistry College Of Arts And Sciences The University Of Tokyo
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Tanaka Toshio
Department Of Cardiology Matsusaka Central General Hospital
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Tanaka Toshio
Department Of Applied Physics Faculty Of Engineering Tokyo University
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Fujita K
Department Of Molecular Toxicology Nagoya City University Graduate School Of Medical Sciences
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Fukamachi Katsumi
Molecular Toxicology Nagoya City University Graduate School Of Medical Sciences
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Usuki Yoshinosuke
Department Of Molecular Materials Science Graduate School Of Science Osaka City University
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Tanaka Toshio
Department of Applied Chemistry, Faculty of Engineering, Osaka Univeristy
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