Studies on Positive Inotropic Agents. II. : Synthesis of(4-Substituted 1-piperazinylcarbonyl)-2-(1H)-quinolinone Derivatives
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概要
- 論文の詳細を見る
Many (1-piperazinylcarbonyl)-2(1H)-quinolinone derivatives were synthesized and examined for positive inotropic activity on the canine heart. Among them, 3,4-dihydro-6-[4-(3-oxo-3-phenylpropyl)-1-piperazinylcarbonyl]-2(1H)-quinolinone (XXIj) and 3,4-dihydro-6-[4-(oxo-4-phenylbutyl)-1-piperazinylcarbonyl]-2(1H)-quinolinone (XXIl) were found to have potent activity.
- 社団法人日本薬学会の論文
- 1986-02-25
著者
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薮内 洋一
大塚製薬徳島研究所
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中川 量之
2nd Tokushima Institute Of New Drugs Research Otsuka Pharmaceutical Co. Ltd.
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中川 量之
大塚製薬株式会社有機化学研究所
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中川 量之
Tokushima Research Institute Otsuka Pharmaceutical Co. Ltd.
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中川 量之
大塚製薬株式会社徳島研究所
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小川 英則
Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd.,
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山下 修司
Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd.,
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富永 道明
Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd.,
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藪内 洋一
Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd.,
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楊 永雄
Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd.,
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藪内 洋一
Tokushima Research Institute Otsuka Pharmaceutical Co. Ltd.
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山下 修司
大塚製薬徳島研究所
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富永 道明
大塚製薬(株)徳島新薬第二研究所
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小川 英則
大塚製薬(株)徳島新薬第二研究所
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楊 永雄
Tokushima Research Institute Otsuka Pharmaceutical Co. Ltd.
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