Synthesis and Pharmacological Evaluation of 7-Substituted Procaterol Derivatives
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概要
- 論文の詳細を見る
A series of procaterol derivatives having a substituent at the 7-position of the carbostyril moiety was synthesized. Halogenation of procaterol and its homologues gave the 7-halogeno derivatives (3). Nitration of the procaterol analogues afforded the 7-nitro derivatives (4), and the catalytic reduction of 4 gave the 7-amino derivatives (5). These compounds showed weak β-adrenoceptor stimulant activities in anesthetized dog.
- 社団法人日本薬学会の論文
- 1993-07-15
著者
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玉田 重晴
Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd.,
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楊 永雄
Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd.,
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吉崎 司郎
(present Address)bio-center Nkk Corporation
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梅里 正七男
Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd.,
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楊 永雄
Tokushima Research Institute Otsuka Pharmaceutical Co. Ltd.
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梅里 正七男
Tokushima Research Institute Otsuka Pharmaceutical Co. Ltd.
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玉田 重晴
Tokushima Research Institute Otsuka Pharmaceutical Co. Ltd.
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