Studies of the Selective O-Alkylation and Dealkylation of Flavonoids. XII. : A New, Convenient Method for Synthesizing 3,5-Dihydroxy-6,7-dimethoxyflavones from 3,5,6,7-Tetramethoxyflavones
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概要
- 論文の詳細を見る
The 5-methoxy group on 3,5,6,7-tetramethoxyflavones and the 3-methoxy group on 3,6,7-trimethoxy-5-tosyloxyflavones were selectively cleaved with anhydrous aluminum bromide in acetonitrile under controlled conditions without the cleavage of benzyloxy groups on the B ring. By the application of these reactions, seven 3,5-dihydroxy-6,7-dimethoxyflavones were easily synthesized from the corresponding 3,5,6,7-tetramethoxyflavones which were synthesized from 3,6-dihydroxy-2,4-ω-trimethoxyacetophenone by means of the Allan-Robinson reaction followed by methylation.
- 社団法人日本薬学会の論文
- 1989-05-25
著者
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津嘉山 正夫
徳島大学工学部
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河村 保彦
徳島大学大学院ソシオテクノサイエンス研究部
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堀江 徳愛
Department of Applied Chemistry, Faculty of Engineering, Tokushima University
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津嘉山 正夫
Department of Applied Chemistry, Faculty of Engineering, Tokushima University
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河村 保彦
Department of Applied Chemistry, Faculty of Engineering, Tokushima University
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吉崎 司郎
(present Address)bio-center Nkk Corporation
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吉崎 司郎
Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd.,
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津嘉山 正夫
Department Of Chemical Science And Technology Faculty Of Engineering The University Of Tokushima
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堀江 徳愛
Department Of Applied Chemistry Faculty Of Engineering Tokushima University
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堀江 徳愛
Department of Chemical Science and Technology, Faculty of Engineering, The University of Tokushima
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