Lythraceous Alkaloids. XIV. Kinetic Equalization of Carbon-13 Nuclear Magnetic Resonance Chemical Shifts in N, O-Dimethyllythranidine, a Cyclophane Bearing Asymmetric Carbon Atoms

スポンサーリンク

概要

• 論文の詳細を見る

• Temperature-dependent carbon-13 nuclear magnetic resonance (^<13>C-NMR) studies have disclosed that the mobile equilibrium in N, O-dimethyllythranidine (1) involves mainly two dynamic processes, which are rotation about the carbon-carbon bond between two phenyl rings and reversal of the piperidine ring. At ambient temperature, ^<13>C chemical shift differences due to rotational movement were averaged, while those due to ring flip of piperidine moiety were not. This provides another example of "selective kinetic equalization of chemical shifts."

• 社団法人日本薬学会の論文
• 1984-01-25

著者

• 藤田 榮一

  Osaka University of Pharmaceutical Sciences

• 山田 敏英

  Tokushima Research Institute Otsuka Pharmaceutical Co. Ltd.

• 冨士 薫

  Institute For Chemical Research Kyoto University

• 藤田 栄一

  京都大学化学研究所

• 藤田 栄一

  Osaka University Of Pharmaceutical Sciences

• 藤田 栄一

  Institute for Chemical Research, Kyoto University

• 山田 敏英

  Institute for Chemical Research, Kyoto University

• 藤田 栄一

  Institute For Chemical Research Kyoto University

関連論文

• The Biological Activities of Podophyllotoxin Compounds
• RADIOSENSITIZING HYPOXIC CELLS WITH NEW 3-NITRO-1,2,4-TRIAZOLE DERIVATIVES IN VITRO AND IN VIVO
• Diastereoselectivity in Addition of Methylmagnesium Halide to Benzoylformate of Chiral 1,1'-Binaphthalene-2,2'-diol
• クロバナヒキオコシIsodon trichocarpus KUDOの生長にともなう各主ジテルペノイド成分の量的変化そのGC, GC-MSによる検討
• Chiral Piperazines as Catalysts for the Enantioselective Addition of Diethylzinc to Aldehydes
• Terpenoids(第31報)Isodon属植物ジテルペノイドのBiogenesisにもとづく分類
• 16 ツルニガクサTeucrium viscidum var. Miquelianumのノルジテルペンについて
• Terpenoids. XXIV. Isolation of Isodonal and Epinodosin from Isodon japonicus and Structure Elucidation of Sodoponin and Epinodosinol, Novel Diterpenoids of the Same Plant
• Terpenoids. XXI. The Structure and Stereochemistry of Isodotricin, a Diterpenoid of Isodon trichocarpus and I. japonicus
• 20 Enmeinの全合成
• 38 Enmein全合成へのapproach
• Terpenoids. XVII. Chemical Conversion of Trichokaurin into Isodocarpin via a Direct Pathway
• Terpenoids(第13報) : Enmeinから誘導される各種立体異性体の薄層クロマトグラフィー
• クロバナヒキオコシ Isodon trichocarpus KUDO の茎の成分研究
• Terpenoids(第6報) : ヒキオコシ Isodon japonicus HARA から Enmein および Enmein 3-acetate の分離について
• The Absolute Configuration of Enmein Transformation of Enmein into (-)-Kaurane
• STRUCTURES OF MAGNOLOSIDES B AND C. NOVEL PHENYLPROPANOID GLYCOSIDES WITH ALLOPYRANOSE AS CORE THE SUGAR UNIT
• Lythraceous Alkaloids. XIV. Kinetic Equalization of Carbon-13 Nuclear Magnetic Resonance Chemical Shifts in N, O-Dimethyllythranidine, a Cyclophane Bearing Asymmetric Carbon Atoms
• Lythraceous Alkaloids. XIII. X-Ray Determination of the Molecular Structures of O-Methyllythranidine N, O, O-Triformate, 22-Bromolythranine N, O, O-Triacetate, and O-Methyldeacetyllythramine
• Lythraceous Alkaloids. XII. Circular Dichroism Studies on Lythranine-Type Alkaloids
• Lythraceous Alkaloids. X. Alkaloids of Lagerstroemia subcostata and L. favriei : A Contribution to the Chemotaxonomy
• Lythraceous Alkaloids. II. The Structure of O-Methyllythranidine
• Lythraceous Alkaloids. I. Characterization of the Novel Alkaloids, Lythranine, Lythranidine, and Lythramine isolated from Lythrum anceps MAKINO
• HYBRIDIZATION OF OLIGODEOXYNUCLEOTIDE WITH REXOD COENZYME MODEL; SYNTHESIS AND PROPERTIES OF THYMIDINE DECAMERS COVALENTLY LINKED TO 5-DEAZAFLAVIN
• Use of 1,1'-Binaphthalene-8,8'-diol as a Chiral Auxiliary for Asymmetric Michael Addition. Application to the Syntheses of Turmeronol A and B
• Spectroscopic Identification of 3-Substituted 4-Methoxycarbonyl-1,3-thiazolidine(or-oxazolidine)-2-thiones and 2-Substituted Thio-4-methoxycarbonyl-Δ^2-1,3-thiazolines(or -oxazolines)
• Substituent Effect of the Benzene Ring on Thermal Rearrangement of the Substituted Benzyl Group from exo-S to N(3) in (rac)2-Substituted Benzylthio-4-methoxycarbonyl-Δ^2-1,3-thiazolines
• Syntheses of (rac)3-Substituted 4-Methoxycarbonyl-1,3-thiazolidine-2-thiones via Rearrangement of a Substituted Group from exo-S to N in (rac)2-Substituted Thio-4-methoxyarbonyl-Δ^2-1,3-thiazolines
• 56 シイタケ菌発育阻害因子,Trichopolynの構造研究
• Cytotoxic Activity of Marine Algae and a Cytotoxic Principle of the Brown Alga Sargassum tortile
• Cytotoxic Triterpenes from a Chinese Medicine, Goreishi
• ENHANCED REACTIVITY OF ZINC ENOLATES OVER LITHIUM ENOLATES IN ASYMMETRIC NITROOLEFINATION
• Design and Synthesis of Antitumor Compounds Based on the Cytotoxic Diterpenoids from the Genus Rabdosia
• A Chiral Synthesis of a Unique Secodehydroabietane from Tall Oil
• Terpenoids. LIV. : The Structures of Rabdoinflexins A and B, New Diterpenoids from Rabdosia inflexa (THUNB.) HARA
• Terpenoids. LIII. : Antitumor Activity of Trichorabdals and Related Compounds
• Terpenoids. LII. : The Structures of Trichorabdal F, Trichorabdal G Acetate, and Trichorabdal H. A Comment on the Structure of Shikodonin
• Terpenoids. LI. : Structures of Antitumor Diterpenoids, Trichorabdals A-E, Isolated from Rabdosia trichocarpa
• THE STRUCTURES OF FOUR NEW DITERPENE ALKALOIDS, SPIRAMINES A, B, C, AND D(Communications to the Editor)
• Terpenoids. L. Antitumor Activity of Diterpenoids from Rabdosia shikokiana var. occidentalis
• Terpenoids. XLVIII. New Diterpenoids from Rabdosia shikokiana var. occidentalis
• Hard Acid and Soft Nucleophile System. VII. A Convenient Reduction of Functionalized Polyarenes to Parent Polyarenes
• ANTITUMOR ACTIVITY OF DITERPENOIDS, TRICHORABDALS A, B, AND C, AND THE RELATED COMPOUNDS : SYNERGISM OF TWO ACTIVE SITES
• RADICAL CATION INDUCED REDUCTIVE DEHALOGENATION OF ORTHO- AND PARA-HALOPHENOLS AND THEIR DERIVATIVES
• Hard Acid and Soft Nucleophile System. VI. A Convenient Synthesis of Alkylthiopolycyclic Aromatics with a Metal Halide and Thiol System
• Studies on the Alkaloids of Thalictrum Thunbergii DC. XVIII. Total Synthesis of optically Active Natural O-Methylthalicberine
• P-1 中国産イチイ科植物Taxus chinensisの新ジテルペノイド(ポスター発表の部)
• ON THE STRUCTURES OF SIX NEW DITERPENOIDS, TAXCHININS E, H, I, J, K AND TAXCHIN B
• SELECTIVE DEMETHYLATION OF ALIPHATIC METHYL ETHER IN THE PRESENCE OF AROMATIC METHYL ETHER WITH THE ALUMINUM CHLORIDE-SODIUM IODIDE-ACETONITRILE SYSTEM
• Terpenoids. XLIX. Reactions of Shikoccin : Oxidation, Catalytic Reduction, and Conversion into the Abietane Skeleton
• THREE NEW 8,9-SECO-ENT-KAURANE DITERPENOIDS FROM RABDOSIA SHIKOKIANA (LABIATAE)
• A Chiral Nonracemic Enolate with Dynamic Axial Chirality: Direct Asymmetric Alkylation of α-Amino Acid Derivatives (SYNTHETIC ORGANIC CHEMISTRY-Fine Organic Synthesis)
• Visualization of Molecular Length of α, ω-Diamines and Temperature by a Receptor Based on Phenolphthalein and Crown Ether (SYNTHETIC ORGANIC CHEMISTRY-Fine Organic Synthesis)
• Synthesis of Extremely Simplified Compounds Possessing the Key Pharmacophore Units of Taxol, Phenylisoserine and Oxetane Moieties
• The First Synthesis of an Optically Active Molecular Bevel Gear with Only Two Cogs on Each Wheel (SYNTHETIC ORGANIC CHEMISTRY-Fine Organic Synthesis)
• 光学活性リン試薬を用いる不斉レフィン化
• Effects of Cholesterol on the Miscibility of Synthetic Glucosamine Diesters in Lipid Bilayers and the Entrapment of Superoxide Dismutase into the Positively Charged Liposomes
• THREE NEW DITERPENOIDS FROM TAXUS CHINENSIS
• Hard Acid and Soft Nucleophile Systems. Part 13. Aluminum Chloride-Sodium Iodide-Acetonitrile System : A Very Mild Reagent for Selective Dealkylation (Commemoration Issue Dedicated to Professor Shigeo Tanimoto On the Occation of His Retirement)
• SYNTHESIS, STRUCTURE, AND SELF-OXIDATION OF ALKYNYL(PHENYL)IODONIUM PERIODATES
• Regioselective Hydroxylation in the C Ring of ent-Kaurene ; Syntheses of ent-11α-Hydroxykaurene and ent-11α-Hydroxykauren-15-one
• Hard Acid and Soft Nucleophile System. IV. Removal of Benzyl Protecting Group with Boron Trifluoride Etherate and Dimethyl Sulflide
• Terpenoids. XXXVII. Hypoiodite Reactions with 6-Hydroxy-17-norkaurane- and 7-Norgibberellane-derivatives
• 22 C_ジベレリンの合成研究
• 13 核間窒素原子を有する二環性アルカロイドの単純化不斉合成(口頭発表の部)
• A CONVENIENT METHOD FOR THE SYNTHESIS OF αβ-UNSATURATED CARBOXYLIC ACID AMIDES UTILIZING A NEW HETERO-BIFUNCTIONAL REAGENT, DMPATT
• Silicon-Assisted Ring Opening of Cyclopropyl Ketones with Boron Trifluoride-Acetic Acid Complex
• Stereoselective Syntheses of E- and Z-9,11-Dodecadien-1-yl Acetates : The Major Sex Pheromones of the Red Bollworm Moth
• Umpolung of Reactivity of Allylsilane, Allylgermane, and Allylstannane via Their Reaction with Thallium (III) Salt : A New Allylation Reaction for Aromatic Compounds
• Umpolung of Reactivity of Allylsilane, Allylgermane, and Allylstannane : Allylation of Aromatic Compounds with Allylmetal and Arylthallium Bis (trifluoroacetate)
• アリルケイ素化合物を用いる有機合成反応--特にアリルカチオン等価体としての有用性 (「有機ケイ素化合物の化学とその応用」特集号)
• Kaurene関連ジテルペンの反応および合成 (天然物化学′80A)
• Terpenoids. XLIII. Total Synthesis of rac-Kaur-16-ene-11α, 15α-diol
• Terpenoids. XLII. A Convenient Stereoselective Transformation of 16-Exocyclic Methylene Group into Carboxy Group in ent-Kaurene and Its 19-Oic Acid
• 28 硝酸タリウム(III)を用いるkaurene型ならびに関連ジテルペン類の酸化および転位反応
• Terpenoids. XXXIII. Chemical Conversion of Enmein into Enmelol
• Terpenoids. XXVI. Structures of Lasiokaurinol and Lasiokaurinin, Two Novel Diterpenoids of Isodon lasiocarpus (HAYATA) KUDO
• Terpenoids. XX. The Structure and Absolute Configuration of Lasiokaurin and Lasiodonin, New Diterpenoids from Isodon lasiocarpus (HAYATA) KUDO
• Iodine (III)-Mediated Intramolecular Cyclization of Hydroxy Allylsilanes : Synthesis of 5- or 6-Membered β-Methylene Cyclic Ethers
• Iodine (III)-Mediated Allylation of Aromatic Compounds and Alcohols Using Allylmetal (Group IVb) Compounds
• Thallium (III)-Mediated Allylation of Alcohols and Carboxylic Acids : Umpolung of Reactivity of Allylmetal (Group IVb) Compounds
• Facile 1,4-Silyl Rearrangement with Concomitant Loss of a Benzenesulfonyl Group : One-Pot Synthesis of Allyloxysilanes
• A New Synthesis of Olefins via the Elimination Reaction of β-Tributylstannyl Organosulfur Compounds
• A New Synthesis of Allyl Nitrates from Allylmetal (Group IVb) Compounds and Thallium (III) Nitrate
• A NEW METHOD FOR REGIOSELECTIVE SYNTHESIS OF α-SUBSTITUTED ALLYLSILANES AND ITS APPLICATION TO THE SYNTHESIS OF E- AND Z-TAGETONES
• Diazidation of Allylsilanes with a Combination of Iodosylbenzene and Trimethylsilyl Azide, and Synthesis of Allyl Azides
• Burgenstock立体化学会議
• A Versatile Synthesis of (±)-Solenopsin A
• The First Example for Cycloenantiomeric Hexahomooxacalix[3]arenes
• The '2+1' Construction of Homooxacalix[3]arenes Possessing Different Substituents on Their Upper Rims
• Preparation of Nitroalkenes : Substitution Reaction via Addition-Elimination Using β-Nitrovinyl Sulfoxides.
• Hard Acid and Soft Nucleophile Systems. Part 12. : Regioselective Functionalization of 1,3-Dienes through the Lewis Acid Mediated Thienium Cation Diels-Alder Reaction.
• Asymmetric Diels-Alder Cycloaddition with Chiral 2-Alkylsulfinyl-1-nitroalkenes.
• PB133 ENANTIOSELECTIVE TOTAL SYNTHESES OF (+)-PODOCARPIC ACID AND RELATED DITERPENOIDS
• Addition-Elimination Strategy for Asymmetric Induction : A Chiral Sulfoxide as a Leaving Group.
• A Formal Asymmetric Synthesis of Calabar Bean Alkaloids
• New Chiral Shift Reagents, Optically Active 2,2'-Dihydroxy-1,1'-binaphthyl and 1,6-Di(o-chlorophenyl)-1,6-diphenylhexa-2,4-diyne-1,6-diol.
• Conformational Difference between Mono- and Diprotonated cis-2,5-Diphenylpiperazinium Salts in the Solid State
• Conformation of 1, 4-Dineopentyl-2, 5-cis-diphenylpiperazinc and Its Diammonium Salts : Remarkable Change in Conformation Depending upon the Counter Anion
• A Total Synthesis of (-)-Physostigmine.

もっと見る 閉じる

スポンサーリンク