Silicon-Assisted Ring Opening of Cyclopropyl Ketones with Boron Trifluoride-Acetic Acid Complex

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概要

• 論文の詳細を見る

• 2-(Trimethylsilylmethyl) cyclopropyl ketones were smoothly cleaved with boron trifluorideacetic acid complex under mild reaction conditions with the assistance of the trimethylsilyl group to give γ, δ-enones in good yields. The major effect of the trimethylsilyl group in the ring opening of the cyclopropyl ketones was unambiguously confirmed in the dicyclopropyl ketone 15 : one of its two cyclopropyl rings, which has a trimethylsilylmethyl group, was selectively cleaved. Furthermore, the reaction was applied to the formal total synthesis of cis-jasmone.

• 公益社団法人日本薬学会の論文
• 1983-11-25

著者

• 落合 正仁

  Institute for Chemical Research, Kyoto University

• 藤田 栄一

  京都大学化学研究所

• 藤田 栄一

  Osaka University Of Pharmaceutical Sciences

• 藤田 栄一

  Institute for Chemical Research, Kyoto University

• 藤田 栄一

  Institute For Chemical Research Kyoto University

• 鷲見 賢三

  Institute for Chemical Research, Kyoto University

• 落合 正仁

  Institute For Chemical Research Kyoto University

• 落合 正仁

  徳島大学大学院ヘルスバイオサイエンス研究部精密薬品製造学分野

• 落合 正仁

  京都大学化学研究所

• 鷲見 賢三

  Institute For Chemical Research Kyoto University

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