Terpenoids. VII. The Structure and Absolute Configuration of Nodosin, a New Diterpenoid from Isodon Species

スポンサーリンク

概要

• 論文の詳細を見る

• Nodosin, a new diterpenoid isolated from Isodon trichocarpus KUDO and I. Japonicus HARA, was converted to the keto lactone acetal X via several steps of reactions. The conversion made it possible to propose the structure II for nodosin. The remaining hydroxyl group proved to be located at C-11 and to have the β-configuration on the basis of a detailed NMR investigation. Thus, the structure and absolute configuration of nodosin were established as formula XIX.

• 社団法人日本薬学会の論文
• 1968-03-25

著者

• 渋谷 雅之

  Institute For Chemical Research Kyoto University

• 藤多 哲朗

  徳島大学薬学部

• 藤田 栄一

  Osaka University Of Pharmaceutical Sciences

• 藤田 栄一

  Institute for Chemical Research, Kyoto University

• 藤多 哲朗

  Institute for Chemical Research, Kyoto University

• 藤田 栄一

  Institute For Chemical Research Kyoto University

関連論文

• The Biological Activities of Podophyllotoxin Compounds
• チョロギStachys sieboldi MIQ.の配糖体成分とそのヒアルロニダーゼ活性に及ぼす影響
• Rabdosia ternifolia(D.DON)HARAの成分 : 新ジテルペンIsodonoic Acidの構造
• Monitored Aminolysis of 3-Acyl-1,3-thiazolidine-2-thiones : Synthesis of Amides and Amide Alkaloids
• 73 非環状アミドアルカロイドならびに大環状ラクタムアルカロイドの新合成研究
• 34 α-Oxo-methylene類の新酸化反応-その生物活性天然物ならびにモデル化合物合成への応用
• 14 抗生物質合成に有用な新しい高選択的不斉誘導
• Terpenoids(第31報)Isodon属植物ジテルペノイドのBiogenesisにもとづく分類
• 16 ツルニガクサTeucrium viscidum var. Miquelianumのノルジテルペンについて
• Terpenoids. XXIV. Isolation of Isodonal and Epinodosin from Isodon japonicus and Structure Elucidation of Sodoponin and Epinodosinol, Novel Diterpenoids of the Same Plant
• Terpenoids. XXI. The Structure and Stereochemistry of Isodotricin, a Diterpenoid of Isodon trichocarpus and I. japonicus
• 20 Enmeinの全合成
• 38 Enmein全合成へのapproach
• Terpenoids. XVII. Chemical Conversion of Trichokaurin into Isodocarpin via a Direct Pathway
• 28 延命草の新微量ジテルペノイドの構造と既知ジテルペノイドの相互変換
• Terpenoids(第13報) : Enmeinから誘導される各種立体異性体の薄層クロマトグラフィー
• 40 カウレン型ジテルペノイドの化学的変換
• Terpenoids. IX. The Structure and Absolute Configuration of Isodocarpin, a New Diterpenoid from Isodon trichocarpus KUDO and I. japonicus HARA
• Terpenoids. VII. The Structure and Absolute Configuration of Nodosin, a New Diterpenoid from Isodon Species
• On the Constituents of Nauclea orientalis L. I. Noreugenin and Naucleoside, A New Glycoside. : Terpenoids V
• クロバナヒキオコシ Isodon trichocarpus KUDO の茎の成分研究
• Terpenoids(第6報) : ヒキオコシ Isodon japonicus HARA から Enmein および Enmein 3-acetate の分離について
• 30 ヒキオコシ,及びクロバナヒキオコシの成分,Isodocarpin,Nodosin,Oridonin,等の化学構造について
• 28.Enmeinの絶対配置 : Enmeinから(-)-Kauraneへの化学的変換
• The Absolute Configuration of Enmein Transformation of Enmein into (-)-Kaurane
• Lythraceous Alkaloids. XIV. Kinetic Equalization of Carbon-13 Nuclear Magnetic Resonance Chemical Shifts in N, O-Dimethyllythranidine, a Cyclophane Bearing Asymmetric Carbon Atoms
• Lythraceous Alkaloids. XIII. X-Ray Determination of the Molecular Structures of O-Methyllythranidine N, O, O-Triformate, 22-Bromolythranine N, O, O-Triacetate, and O-Methyldeacetyllythramine
• Lythraceous Alkaloids. XII. Circular Dichroism Studies on Lythranine-Type Alkaloids
• Lythraceous Alkaloids. X. Alkaloids of Lagerstroemia subcostata and L. favriei : A Contribution to the Chemotaxonomy
• Lythraceous Alkaloids. II. The Structure of O-Methyllythranidine
• Lythraceous Alkaloids. I. Characterization of the Novel Alkaloids, Lythranine, Lythranidine, and Lythramine isolated from Lythrum anceps MAKINO
• 1 ミソハギのアルカロイド,lythranine,lythranidineおよびlythramineの構造
• シイタケを病気にするキノコの話 : オオボタンタケの活性成分
• Cytotoxic Activity of Marine Algae and a Cytotoxic Principle of the Brown Alga Sargassum tortile
• Cytotoxic Triterpenes from a Chinese Medicine, Goreishi
• Terpenoids. LIII. : Antitumor Activity of Trichorabdals and Related Compounds
• Terpenoids. LII. : The Structures of Trichorabdal F, Trichorabdal G Acetate, and Trichorabdal H. A Comment on the Structure of Shikodonin
• Terpenoids. LI. : Structures of Antitumor Diterpenoids, Trichorabdals A-E, Isolated from Rabdosia trichocarpa
• Terpenoids. L. Antitumor Activity of Diterpenoids from Rabdosia shikokiana var. occidentalis
• Terpenoids. XLVIII. New Diterpenoids from Rabdosia shikokiana var. occidentalis
• Hard Acid and Soft Nucleophile System. VII. A Convenient Reduction of Functionalized Polyarenes to Parent Polyarenes
• ANTITUMOR ACTIVITY OF DITERPENOIDS, TRICHORABDALS A, B, AND C, AND THE RELATED COMPOUNDS : SYNERGISM OF TWO ACTIVE SITES
• RADICAL CATION INDUCED REDUCTIVE DEHALOGENATION OF ORTHO- AND PARA-HALOPHENOLS AND THEIR DERIVATIVES
• Hard Acid and Soft Nucleophile System. VI. A Convenient Synthesis of Alkylthiopolycyclic Aromatics with a Metal Halide and Thiol System
• Studies on the Alkaloids of Thalictrum Thunbergii DC. XVIII. Total Synthesis of optically Active Natural O-Methylthalicberine
• SELECTIVE DEMETHYLATION OF ALIPHATIC METHYL ETHER IN THE PRESENCE OF AROMATIC METHYL ETHER WITH THE ALUMINUM CHLORIDE-SODIUM IODIDE-ACETONITRILE SYSTEM
• Terpenoids. XLIX. Reactions of Shikoccin : Oxidation, Catalytic Reduction, and Conversion into the Abietane Skeleton
• THREE NEW 8,9-SECO-ENT-KAURANE DITERPENOIDS FROM RABDOSIA SHIKOKIANA (LABIATAE)
• Antitumor Activity of Rabdosia and Teucrium Diterpenoids against P 388 Lymphocytic Leukemia in Mice
• Hard Acid and Soft Nucleophile System. IV. Removal of Benzyl Protecting Group with Boron Trifluoride Etherate and Dimethyl Sulflide
• Terpenoids. XXXVII. Hypoiodite Reactions with 6-Hydroxy-17-norkaurane- and 7-Norgibberellane-derivatives
• 22 C_ジベレリンの合成研究
• Absolute Configuration of Lythrancine-I, -II, -III, -IV, Lythrancepine-I, -II, and -III
• 12 ミソハギの新塩基Lythrancine-I〜IV及びLythrancepine-I〜IIIの構造について
• Silicon-Assisted Ring Opening of Cyclopropyl Ketones with Boron Trifluoride-Acetic Acid Complex
• Stereoselective Syntheses of E- and Z-9,11-Dodecadien-1-yl Acetates : The Major Sex Pheromones of the Red Bollworm Moth
• Umpolung of Reactivity of Allylsilane, Allylgermane, and Allylstannane via Their Reaction with Thallium (III) Salt : A New Allylation Reaction for Aromatic Compounds
• Umpolung of Reactivity of Allylsilane, Allylgermane, and Allylstannane : Allylation of Aromatic Compounds with Allylmetal and Arylthallium Bis (trifluoroacetate)
• Kaurene関連ジテルペンの反応および合成 (天然物化学′80A)
• Terpenoids. XLIII. Total Synthesis of rac-Kaur-16-ene-11α, 15α-diol
• Terpenoids. XLII. A Convenient Stereoselective Transformation of 16-Exocyclic Methylene Group into Carboxy Group in ent-Kaurene and Its 19-Oic Acid
• 28 硝酸タリウム(III)を用いるkaurene型ならびに関連ジテルペン類の酸化および転位反応
• Terpenoids. XXXIII. Chemical Conversion of Enmein into Enmelol
• Terpenoids. XXVI. Structures of Lasiokaurinol and Lasiokaurinin, Two Novel Diterpenoids of Isodon lasiocarpus (HAYATA) KUDO
• Iodine (III)-Mediated Intramolecular Cyclization of Hydroxy Allylsilanes : Synthesis of 5- or 6-Membered β-Methylene Cyclic Ethers
• Iodine (III)-Mediated Allylation of Aromatic Compounds and Alcohols Using Allylmetal (Group IVb) Compounds
• Thallium (III)-Mediated Allylation of Alcohols and Carboxylic Acids : Umpolung of Reactivity of Allylmetal (Group IVb) Compounds
• Facile 1,4-Silyl Rearrangement with Concomitant Loss of a Benzenesulfonyl Group : One-Pot Synthesis of Allyloxysilanes
• A New Synthesis of Olefins via the Elimination Reaction of β-Tributylstannyl Organosulfur Compounds
• A New Synthesis of Allyl Nitrates from Allylmetal (Group IVb) Compounds and Thallium (III) Nitrate
• A NEW METHOD FOR REGIOSELECTIVE SYNTHESIS OF α-SUBSTITUTED ALLYLSILANES AND ITS APPLICATION TO THE SYNTHESIS OF E- AND Z-TAGETONES
• New Allylation Reaction using Allylmetal (Group IVb) Compounds : Synthesis of N-Allylamides
• Reactions of Enmein-type Compounds with Lead Tetraacetate Iodine under Irradiation
• Diazidation of Allylsilanes with a Combination of Iodosylbenzene and Trimethylsilyl Azide, and Synthesis of Allyl Azides
• プロキラルなσ-対称分子への高選択的不斉誘導 (精密合成化学--21世紀を担う若い化学者へ)
• スペルミジンシデロホア,パラバクチンの全合成(発表論文抄録(1984年),福山大学開学10周年記念号)
• メソ化合物,プロキラル炭素を含む化合物からの光学活性体の合成
• 62 機能性複素五員環を活用するVirginiamycin M2の全合成研究
• Antitumor Activity of Acylated Oridonin
• An Efficient Method for Selective Acetylation of Alcoholic Hydroxyl Groups
• 62 Spermidine siderophoresの全合成研究
• 47 大環状スペルミジンアルカロイドの新全合成
• Utilization of Derivatives of Thiazolidine-2-thione : Esterification
• 含硫黄脱離基を活用する新有機合成
• Useful Dethioacetalization with Soft Acid Metal Salts : Thallium Trinitrate and Mercuric Perchlorate
• The Antitumor and Antibacterial Activity of the Isodon Diterpenoids
• Dethioacetalization with Thallium (III) Nitrate
• テルペノイド(第23報)カウレンのヒドラジン-ヒドラジン塩酸塩での還元
• Burgenstock立体化学会議
• オクテット
• 有機合成における保護基 : その最近の進歩
• A Versatile Synthesis of (±)-Solenopsin A
• メリットを生かして合理的な運用を(ポスターセッションを考える)
• 6 グラヤノトキシン類の合成研究
• アリルケイ素化合物を用いる有機合成反応 : 特にアリルカチオン等価体としての有用性
• 生理活性物質に対する新しい合成戦略 (新しい有機合成の展望--第一線化学者の考え方・進め方)
• 高選択的不斉誘導法
• 若干の大環状アルカロイドの合成
• Total Synthesis of Optically Active Natural O-Methylthalicberine
• サツマイナモリ Ophiorrhiza japonica B_L. の成分研究

もっと見る 閉じる

スポンサーリンク