A New Synthesis of Olefins via the Elimination Reaction of β-Tributylstannyl Organosulfur Compounds

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概要

• 論文の詳細を見る

• Organosulfur compounds on treatment with butyllithium in tetrahydrofuran followed by tributylstannylmethyl iodide 1 afforded olefins. The reaction was found to proceed via the destannylsulfurization of the initially formed β-stannyl organosulfur compounds. Thus, allyl 2-pyridyl sulfides 2 or allyl phenyl sulfones 12 were converted into 1,3-dienes 4. Compounds 13 and 15 were converted into the olefins 14 and 17. Furthermore, the reaction was applied to the synthesis of α-substituted vinyl sulfides 24 and allene 27. The stereochemistry of the double bond is discussed.

• 公益社団法人日本薬学会の論文
• 1984-05-25

著者

• 藤田 榮一

  Osaka University of Pharmaceutical Sciences

• 落合 正仁

  Institute for Chemical Research, Kyoto University

• 藤田 栄一

  京都大学化学研究所

• 藤田 栄一

  Osaka University Of Pharmaceutical Sciences

• 藤田 榮一

  Institute for Chemical Research, Kyoto University

• 浮田 辰三

  Institute for Chemical Research, Kyoto University

• 但田 信一

  Research Laboratories, Nippon Shinyaku Co., Ltd.

• 落合 正仁

  Institute For Chemical Research Kyoto University

• 落合 正仁

  徳島大学大学院ヘルスバイオサイエンス研究部精密薬品製造学分野

• 浮田 辰三

  Institute For Chemical Research Kyoto University

• 但田 信一

  日本新薬

• 落合 正仁

  京都大学化学研究所

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