Terpenoids. L. Antitumor Activity of Diterpenoids from Rabdosia shikokiana var. occidentalis

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概要

• 論文の詳細を見る

• In vitro antitumor activity of diterpenoids isolated from Rabdosia shikokiana var. occidentalis was determined against HeLa cells. Some of these compounds possess considerable activity against Ehrlich ascites carcinoma inoculated into mice. In particular, the epoxyketone 7 derived from shikoccin (1) showed potent activity. The in vivo activity of shikoccin (1) against six tumor lines was evaluated.

• 公益社団法人日本薬学会の論文
• 1985-03-25

著者

• 武田 節夫

  Tokushima Institute, Taiho Pharmaceutical Co., Ltd.,

• 武田 節夫

  Research Institute, Taiho Pharmaceutical Co., Ltd.,

• 野出 学

  Kyoto Pharmaceutical University

• 野出 学

  Institute For Chemical Research Kyoto University

• 藤田 榮一

  Osaka University of Pharmaceutical Sciences

• 冨士 薫

  Institute For Chemical Research Kyoto University

• 藤田 栄一

  京都大学化学研究所

• 伊藤 望

  Research Laboratories Nippon Shoji Kaisha Ltd.

• 藤田 栄一

  Osaka University Of Pharmaceutical Sciences

• 藤田 榮一

  Institute for Chemical Research, Kyoto University

• 釆見 憲男

  Research Laboratory, Taiho Pharmaceutical Co., Ltd.

• 采見 憲男

  Tokushima Institute Taiho Pharmaceutical Co. Ltd.

• 釆見 憲男

  Research Laboratory Taiho Pharmaceutical Co. Ltd.

• 武田 節夫

  Tokushima Institute Taiho Pharmaceutical Co. Ltd.

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