Synthesis of Extremely Simplified Compounds Possessing the Key Pharmacophore Units of Taxol, Phenylisoserine and Oxetane Moieties

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概要

• 論文の詳細を見る

• Straight chain compounds having a phenylisoserine unit and an oxetane ring at the α- and ω-position, respectively as extremely simplified analogues of taxol were prepared. None of these compounds showed promising tubulin inhibitory activity.

• 公益社団法人日本薬学会の論文
• 1999-09-15

著者

• 冨士 薫

  Institute For Chemical Research Kyoto University

• Kohno Michiaki

  School Of Pharmaceutical Sciences Nagasaki University

• FUJI KAORU

  Institute for Chemical Research, Kyoto University

• NURUZZAMAN Mohammad

  Institute for Chemical Research, Kyoto University

• WATANABE Yukari

  Institute for Chemical Research, Kyoto University

• OHTSUBO Tadamune

  Institute for Chemical Research, Kyoto University

• HAMAJIMA Yoshio

  Institute for Chemical Research, Kyoto University

• Fuji Kaoru

  Institute For Chemical Research Kyoto University

• Nuruzzaman Mohammad

  Institute For Chemical Research Kyoto University

• Watanabe Yukari

  Institute For Chemical Research Kyoto University

• Hamajima Yoshio

  Institute For Chemical Research Kyoto University

• Ohtsubo T

  Institute For Chemical Research Kyoto University

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