Chiral Piperazines as Catalysts for the Enantioselective Addition of Diethylzinc to Aldehydes
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概要
- 論文の詳細を見る
Enantioselective ethylation of benzaldehyde with diethylzinc in the presence of a catalytic amount of chiral piperazine derivatives was investigated. The chiral piperazine works as an asymmetric catalyst in the alkylation, yielding 1-phenylpropanol with a moderate enantioselectivity. The influence of structural variation of the piperazine ring upon the asymmetric induction and the mechanism involved are discussed.
- 社団法人日本薬学会の論文
- 1993-09-15
著者
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宮本 寿
大塚製薬株式会社微生物研究所
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冨士 薫
Institute For Chemical Research Kyoto University
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田中 圭
静岡県大 薬
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田中 圭
Institute for Chemical Research, Kyoto University
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宮本 寿
Institute for Chemical Research, Kyoto University
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田中 圭
京都大学薬学部
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