A Formal Asymmetric Synthesis of Calabar Bean Alkaloids
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概要
- 論文の詳細を見る
A total synthesis of (-)-eserethole (2) has been accomplished using the Diels-Alder reaction of (S)-(-)-2-methyl-2-[2-(E)-nitroethenyl]-δ-valerolactone (3) and Danishefsky's diene as a key step. The synthesis of optically pure (-)-eserethole (2) constitutes a formal synthesis of naturaly occurring Calabar bean alkaloids, such as (-)-physostigmine (1), (-)-physovenine (17) and (-)-geneserine (18).
- 公益社団法人日本薬学会の論文
- 1996-04-15
著者
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冨士 薫
Institute For Chemical Research Kyoto University
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Hao X‐j
Kunming Institute Of Botany Academia Sinica
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FUJI KAORU
Institute for Chemical Research, Kyoto University
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Fuji Kaoru
Institute For Chemical Research Kyoto University
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Node Manabu
Department Of Pharmaceutical Manufacturing Chemistry 21st Century Coe Program Kyoto Pharmaceutical U
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Node M
Department Of Pharmaceutical Manufacturing Chemistry 21st Century Coe Program Kyoto Pharmaceutical U
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Node Manabu
Kyoto Pharmaceutical Univ.
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Node Manabu
Department Of Pharmaceutical Manufacturing Chemistry Kyoto Pharmaceutical University
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NISHIDE Kiyoharu
Kyoto Pharmaceutical University
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HAO Xiao-jiang
Kunming Institute of Botany, Academia Sinica
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Nishide Kiyoharu
Department Of Pharmaceutical Manufacturing Chemistry 21st Century Coe Program Kyoto Pharmaceutical U
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Nishide K
Kyoto Pharmaceutical University
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Node Manabu
Department Of Pharmaceutical Manufacturing Chemistry 21st Century Coe Program Kyoto Pharmaceutical U
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Nishide Kiyoharu
Department Of Pharmaceutical Manufacturing Chemistry 21st Century Coe Program Kyoto Pharmaceutical U
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