NEW ASYMMETRIC SYNTHESES OF (-)-ISOIRIDOMYRMECIN AND (+)-LOGANIN AGLUCON 6-ACETATE UTILIZING C_2-SYMMETRIC DIMETHYL 3,7-DIHYDROXY-CIS-BICYCLO[3.3.0]OCTA-2,6-DIENE-2,6-DICARBOXYLATE
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概要
- 論文の詳細を見る
The first asymmetric synthesis of (-)-isoiridomyrmecin and formal synthesis of (-)-loganin were done using chiral C_2-symmetric building block dimethyl 3,7-dihydroxy-cis-bicyclo[3.3.0]octa-2,6-diene-2,6-dicarboxylate (2) which was prepared by the lipase-catalyzed asymmetric demethoxy-carbonylation of tetramethyl 3,7-dioxo-cis-bicyclo-[3.3.0]octane-2,4,6,8-tetracarboxyrate (1).
- 公益社団法人日本薬学会の論文
- 1998-04-15
著者
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Node Manabu
Kyoto Pharmaceutical Univ.
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Node Manabu
Kyoto Pharmaceutical University
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Araki Mamoru
Kyoto Pharmaceutical University
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NISHIDE Kiyoharu
Kyoto Pharmaceutical University
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TANAKA Hiroaki
Kyoto Pharmaceutical University
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NAKAMURA Daisaku
Kyoto Pharmaceutical University
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INOUE Takehisa
Kyoto Pharmaceutical University
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