Preparation and Application of Odorless 1,3-Propanedithiol Reagents
スポンサーリンク
概要
- 論文の詳細を見る
2-Dodecyl-1,3-propanedithiol (2a) was prepared without a malodorous procedure as an odorless reagent that was usable in place of 1,3-propanedithiol (1) in organic reactions, e.g., in the reduction of azides and protection of carbonyl groups. The 1,3-dithioacetals obtained in the latter reaction were effectively reduced to methylene with Raney nickel and reconverted to the original carbonyl compounds by hydrolysis with N-bromosuccinimide in aqueous 2-butanone. In addition, the anion of 1,3-dithiane prepared from 2a and formaldehyde could be utilized as a synthetic equivalent of an anionic carbonyl carbon.
- 公益社団法人日本薬学会の論文
- 2006-01-01
著者
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Katoh Takahiro
Department Of Pharmaceutical Manufacturing Chemistry 21st Century Coe Program Kyoto Pharmaceutical U
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梶本 哲也
京都薬大
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KAJIMOTO Tetsuya
Department of Pharmaceutical Manufacturing Chemistry, Kyoto Pharmaceutical University
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NODE Manabu
Department of Pharmaceutical Manufacturing Chemistry, Kyoto Pharmaceutical University
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Node Manabu
Department Of Pharmaceutical Manufacturing Chemistry 21st Century Coe Program Kyoto Pharmaceutical U
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Node M
Department Of Pharmaceutical Manufacturing Chemistry 21st Century Coe Program Kyoto Pharmaceutical U
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Node Manabu
Kyoto Pharmaceutical Univ.
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NISHIDE Kiyoharu
Department of Pharmaceutical Manufacturing Chemistry, 21st Century COE Program, Kyoto Pharmaceutical
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Katoh Takahiro
Department Of Pharmaceutical Manufacturing Chemistry Kyoto Pharmaceutical University
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Kajimoto Tetsuya
Department Of Biotechnology Tokyo University Of Agriculture And Technology
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MATOBA Manabu
Department of Pharmaceutical Manufacturing Chemistry, 21st Century COE Program, Kyoto Pharmaceutical
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Matoba Manabu
Department Of Pharmaceutical Manufacturing Chemistry 21st Century Coe Program Kyoto Pharmaceutical U
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Kajimoto Tetsuya
Department Of Pharmaceutical Manufacturing Chemistry Kyoto Pharmaceutical University
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Nishide Kiyoharu
Department Of Pharmaceutical Manufacturing Chemistry 21st Century Coe Program Kyoto Pharmaceutical U
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Nishide K
Kyoto Pharmaceutical University
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Node Manabu
Department Of Pharmaceutical Manufacturing Chemistry 21st Century Coe Program Kyoto Pharmaceutical U
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Kato Takahiro
Department Of Pharmaceutical Manufacturing Chemistry Kyoto Pharmaceutical University
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Nishide Kiyoharu
Department Of Pharmaceutical Manufacturing Chemistry 21st Century Coe Program Kyoto Pharmaceutical U
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