The First Example for Cycloenantiomeric Hexahomooxacalix[3]arenes

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概要

• 論文の詳細を見る

• Cycloenantiomeric hexahomooxacalix[3]arenes with different substituents on the three upper rims were synthesized for the first time by fixing their conformation into a cone. A cycloenantiomeric hexahomooxacalix[3]arene 6 was resolved into both enantiomeric forms and chiroptically characterized. Preliminary ^1H-NMR studies indicated that the optically resolved cycloenantiomer 6 could discriminate the enantiomers of hydrochloride of phenylalanine ethyl ester.

• 公益社団法人日本薬学会の論文
• 2001-04-01

著者

• Kinoshita T

  Exploratory Research Laboratoeis Fujisawa Pharmaceutical Co. Ltd.

• Kinoshita Takayoshi

  Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.

• 冨士 薫

  Institute For Chemical Research Kyoto University

• FUJI KAORU

  Institute for Chemical Research, Kyoto University

• TSUBAKI Kazunori

  Institute for Chemical Research, Kyoto University

• KAWADA MITSURU

  Pharmaceutical Research Division, Takeda Chemical Industries Ltd.

• Tsubaki K

  Institute For Chemical Research Kyoto University

• Fuji Kaoru

  Institute For Chemical Research Kyoto University

• Kawada Mitsuru

  Pharmaceutical Research Division Takeda Chemical Industries Ltd.

• OTSUBO Tadamune

  Institute for Chemical Research, Kyoto University

• Kinoshita Takayoshi

  Exploratory Research Laboratoeis Fujisawa Pharmaceutical Co. Ltd.

• Otsubo Tadamune

  Institute For Chemical Research Kyoto University

• 嶽 一彦

  New Drug Research Laboratories Fujisawa Pharmaceutical Co. Ltd.

• Tsubaki Kazunori

  Institute For Chemical Research Kyoto University

• KAWADA Mitsuru

  Pharmaceutical Research Division, Takeda Chemical Industries, Ltd.

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