ANTITUMOR ACTIVITY OF DITERPENOIDS, TRICHORABDALS A, B, AND C, AND THE RELATED COMPOUNDS : SYNERGISM OF TWO ACTIVE SITES

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概要

• 論文の詳細を見る

• Antitumor activity of Rabdosia diterpenoids and the related compounds against Ehrlich ascites carcinoma has been studied. In addition to α-methylene cyclopentanone moiety, spirolactone aldehyde grouping functions as an active site in these compounds. Significant increase in activity can be attributed to synergism of two active sites in the molecule.

• 公益社団法人日本薬学会の論文
• 1983-04-25

著者

• 武田 節夫

  Tokushima Institute, Taiho Pharmaceutical Co., Ltd.,

• 野出 学

  Kyoto Pharmaceutical University

• 野出 学

  Institute For Chemical Research Kyoto University

• 藤田 栄一

  京都大学化学研究所

• 藤田 栄一

  Osaka University Of Pharmaceutical Sciences

• 藤田 栄一

  Institute for Chemical Research, Kyoto University

• 佐井 みどり

  Faculty of Pharmaceutical Sciences, Setsunan University

• 釆見 憲男

  Research Laboratory, Taiho Pharmaceutical Co., Ltd.

• 藤田 栄一

  Institute For Chemical Research Kyoto University

• 采見 憲男

  Tokushima Institute Taiho Pharmaceutical Co. Ltd.

• 釆見 憲男

  Research Laboratory Taiho Pharmaceutical Co. Ltd.

• 武田 節夫

  Tokushima Institute Taiho Pharmaceutical Co. Ltd.

• 佐井 みどり

  Faculty Of Pharmaceutical Sciences Setsunan University

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