Deoxysugar Synthesis. I. Lithium-ethylamine Reduction of Carbohydrate Phosphorodiamidates
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概要
- 論文の詳細を見る
Following the procedure of Ireland, et al., 3-phosphorodiamidates (1b and 6b) of 1,2 : 5,6-di-O-isopropylidene-glucose and -allose were treated with lithium-ethylamine to give a 2,3-dideoxy compound (3) in good yield, while similar treatment of a glucosaminide 3-phosphorodiamidate (11b) yielded a 3-deoxy derivative (12a). Thus, this method has the advantage of convenience for the preparation of deoxysugars.
- 社団法人日本薬学会の論文
- 1975-07-25
著者
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大木 英二
Central Research Laboratories, Sankyo Co., Ltd.
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老田 貞夫
Central Research Laboratories, Sankyo Co., Ltd.
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大橋 芳彦
Central Research Laboratories, Sankyo Co., Ltd.
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大橋 芳彦
Central Research Laboratories Sankyo Co. Ltd.
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佐伯 博道
Central Research Laboratories, Sankyo Co., Ltd.
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大木 英二
Research Laboratory Zenyaku Kogyo Co. Ltd.
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大木 英二
Central Research Laboratories Sankyo Co. Ltd.
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老田 貞夫
Medicinal Chemistry Research Laboratories Sankyo Co. Ltd.
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佐伯 博道
Central Research Laboratories Sankyo Co. Ltd.
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