Triazole Antifungals. III. Stereocontrolled Synthesis of an Optically Active Triazolylmethyloxirane Precursor to Antifungal Oxazolidine Derivatives
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概要
- 論文の詳細を見る
Stereocontrolled syntheses of an optically active triazolymethyloxirane 2,an important intermediate for the preparation of anifungal oxazolidine compounds 1,was achieved by two methods using L-lactic acid as a starting material. The key intermediate ketone 6 used in the procedures also served for the synthesis of the enantiomer of 2 and the corresponding diastereomeric epoxide.
- 社団法人日本薬学会の論文
- 1991-09-25
著者
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宮岡 武男
Medicinal Chemistry Research Laboratories Sankyo Co. Ltd.
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鴻巣 俊之
Medicinal Chemistry Research Laboratories, Sankyo Co., Ltd.,
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田島 和
Medicinal Chemistry Research Laboratories, Sankyo Co., Ltd.,
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老田 貞夫
Medicinal Chemistry Research Laboratories, Sankyo Co., Ltd.,
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田島 和
Medicinal Chemistry Research Laboratories Sankyo Co. Ltd.
-
老田 貞夫
Medicinal Chemistry Research Laboratories Sankyo Co. Ltd.
-
鴻巣 俊之
Medicinal Chemistry Research Laboratories Sankyo Co. Ltd.
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鴻巣 俊之
Medicinal Chemistry Res. Laboratories Ii Daiichi Sankyo Co. Ltd.
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