Selective O-Benzoylation in Aminoglycoside Antibiotics

スポンサーリンク

概要

• 論文の詳細を見る

• It was shown that the 3'and 4'hydroxy groups of N-protected butirosin or kanamycin derivatives resist benzoylation in an aqueous medium, furnishing an effective method for chemical modifications of these antibiotics.

• 社団法人日本薬学会の論文
• 1977-08-25

著者

• 大木 英二

  Central Research Laboratories, Sankyo Co., Ltd.

• 林 輝雄

  Chemical Research Laboratories Sankyo Co. Ltd.

• 佐伯 博道

  Central Research Laboratories, Sankyo Co., Ltd.

• 島田 芳和

  Central Research Laboratories, Sankyo Co., Ltd.

• 大木 英二

  Research Laboratory Zenyaku Kogyo Co. Ltd.

• 大木 英二

  Central Research Laboratories Sankyo Co. Ltd.

• 林 輝雄

  Central Research Laboratories, Sankyo Co., Ltd.

• 武田 憲子

  Central Research Laboratories, Sankyo Co., Ltd.

• 武田 憲子

  Medical Chemistry Research Laboratories Sankyo Co. Ltd.

• 島田 芳和

  Central Research Laboratories Sankyo Co. Ltd.

• 佐伯 博道

  Central Research Laboratories Sankyo Co. Ltd.

関連論文

• 3,5-Propanopiperidine Derivatives as Potential Analgesics
• 3-Azabicyclo [3. 3. 1] nonane Derivatives as Potential Analgesics
• Triazole Antifungals. IV. Synthesis and Antifungal Activities of 3-Acylamino-2-aryl-2-butanol Derivatives
• Triazole Antifungals. II. : Synthesis and Antifungal Activities of 3-Acyl-4-methyloxazolidine Derivatives
• Deoxysugar Synthesis. I. Lithium-ethylamine Reduction of Carbohydrate Phosphorodiamidates
• Synthesis of 3', 4'-Dideoxybutirosin A, Active against Butirosin Resistant Bacteria
• Synthetic Study of Siccanin, an Antifungal Antibiotic. III. Some Diels-Alder Adducts of 2-Methoxy-5-methoxycarbonylbenzoquinone
• Synthetic Study of Siccanin, an Antifungal Antibiotic. II. An Attempt to Synthesis of Siccanin Skeleton
• Synthetic Study of Siccanin, an Antifungal Antibiotic. I. Synthesis of 3,5a-Dimethyl-1-hydroxy-5,5a, 6,7,8,8a-hexahydroxanthene
• Conformational Study of 3,4-Epiminopyrrolidines in Solution
• Studies on Bi-heterocyclic Compounds. II. : 5-Substituted Thiazolones
• Studies on Bi-heterocyclic Compounds. I. 6-Substituted Dihydro-1,4-thiazinones(Organic,Chemical)
• NEW SYNTHESIS OF PENEMS VIA A REDUCTIVE CYCLIZATION REACTION OF OXALIMIDES WITH TRIALKYL PHOSPHITE
• Studies on Heterocyclic Enaminonitriles. III. Reactions of 2-Benzamido-3-cyano-4,5-dihydrothiophenes with Amines
• 2-(Alkylthio) penem-3-carboxylic Acids. V. Synthesis and Antibacterial Activities of "1-Thiathienamycin"and Related Compounds
• 2-(Alkylthio) penem-3-carboxylic Acids. IV. Synthesis of (Hydroxyethyl)-azetidinone Precursors to 1-Thia Analogs of Thienamycin
• 2-(Alkylthio) penem-3-carboxylic Acids. III. Synthesis of 6-Ethylpenems
• Synthetic Approach directed at 1-Carbapenems and 1-Carbapenams
• 2-(Alkylthio) penem-3-carboxylic Acids. II. Chemical Manipulation of Penem Side Chains
• 2-(Alkylthio) penem-3-carboxylic Acids. I. Synthesis of 6-Unsubstituted Penems
• Deoxysugar Synthesis. IV. Deoxygenation of Aminoglycoside Antibiotics through Reduction of Their Dithiocarbonates
• Synthesis of Oxapenam Derivatives
• Deoxysugar Synthesis. III. Removal of Vicinal Mesyloxy Groups with Naphthalene-Sodium
• Selective O-Benzoylation in Aminoglycoside Antibiotics
• Dihydrothiazine Ring-Opening Reactions in 2-Alkoxycephalosporin Compounds
• Deoxysugar Synthesis. II. Deoxygenations of Methyl 2,6-Dibenzyloxy-carbonylamino-2,6-dideoxy-α-D-glucopyranoside
• Opening of the Cephalosporin Dihydrothiazine Ring
• A New Rearrangement Reaction of 2-Methylthiolated Cephem Derivatives
• Methylthiolated Cephem Derivatives
• Chemical Studies on Azalomycins. III. Alkaline Degradation of Azalomycin-B.
• Chemical Studies on Azalomycins. I. Preliminary Study on Azalomycin-B.
• 13 アザロマイシンBの構造研究
• Chemical Studies on Azalomycins. II. Sugar Component of Azalomycin-B.
• Triazole Antifungals. V. Synthesis and Antifungal Activities of Some Amides Related to 3-Acylamino-2-aryl-1-triazolyl-2-butanol
• Synthesis and Antifungal Activities of Some Thiolane-Triazole Derivatives
• セフェム化合物のアルキル化〔英文〕
• Syntheses of Neamine Derivatives and Their Antibacterial Activities
• An Alternate Synthesis of Leupeptins and Their Analogs
• 抗カビ剤シッカニンの合成研究-4-シッカニンホスホアミデ-トのアルカリ金属還元〔英文〕
• Total Synthesis of dl-Anisomycin
• Syntheses of 3,4-Epoxy- and 3,4-Epimino-pyrrolidines
• Synthesis of 4,5-Epiminotetrahydro-1,2-oxazine
• Syntheses of 3,4-Epiminopyrrolidine and 4,5-Epiminotetrahydro-1,2-oxazine
• Syntheses of Some Branched-chain Nitrocycloalkanols
• 1,3-Dipolar Cycloaddition Reaction of Aziridinedicarboximide
• Syntheses of Tricyclic Amines from Azabicyclic Compounds through Carbenes
• Total Synthesis of dl-Anisomycin
• The Studies on Quinolizinium Salts. II. Ring Opening Reactions of Quinolizinium Bromide by Grignard Reagents
• ragmentation Reaction of Azabicyclic Compounds
• 1 6,7-エピイミノヘプトーズの合成及びリンコサミンに関する合成研究
• Nitromethane-Condensation Reaction with 5-Aldehydes of Pentodialdofuranosides
• Syntheses of 2,3-Di-O-benzyl-α-L-arabino-pentodialdo-1,4-furanoside and Its β-Anomer
• Conversion of D-Glucofuranose to L-arabino-Hexofuranoside
• Syntheses of 5,6-Aziridino Sugars
• Benzylation of Carbohydrate Derivatives in Dimethyl Sulfoxide.
• Rearrangement of D-glucofuranoside to L-Arabino-hexofuranoside : Synthesis of 6-Deoxy-6-nitro-L-arabino-hexofuranoside through L-Arabino-pentodialdo-1,4-furanoside from D-Glucose or L-Arabinose
• 5 ロイペプチンおよびその同族体の合成研究
• Synthesis of N-Acetyllincosamine
• Synthesis of N-Acetyllincosamine
• Synthesis of 6,7-Dideoxy-6,7-epimino-1,2 : 3,4-di-O-isopropylidene-D (and L)-glycero-α-D-galacto-heptopyranose and Its Conversion into 6-Amino-6-deoxyheptose
• Effect of 3-Hydroxyl Group on 5,6-Epimine Formation in 1,2-O-Isopropylideneglucofuranose
• 5,6-Epimino-D-glucofuranose and Synthesis of Nojirimycin (5-Amino-5-deoxyglucose)
• Syntheses and Characterizations of 5,6-Epimino-L-altro-and -L-idofuranoses
• 5 5,6-アチリジノ糖および抗生物貭ノジリマイシンの合成
• Synthesis of Nojirimycin, D-Glucopiperidinose

もっと見る 閉じる

スポンサーリンク