Studies on Decomposition and Stabilization of Drugs in Solution. VII. Stabilization of Methantheline Bromide in Aqueous Solution by Surface-active Agents.
スポンサーリンク
概要
- 論文の詳細を見る
1) The prevention of hydrolysis of ester, using methantheline bromide (Banthine) as an example, with surfactants was examined. Surfactants used were anionic, cationic, and nonionic. Anionic surfactant (sodium laurylsulfate) markedly prevented the hydrolysis (the half life becomes 100 times longer in 0.5% laurylsulfate solution) and nonionic surfactant prevents it slightly. 2) Hydrolysis in sodium laurylsulfate solution does not follow a pseudo-first order course and is influenced by a buffer concentration. 3) The higher the concentration of sodium laurylsulfate, the slower became the hydrolysis.
- 公益社団法人日本薬学会の論文
- 1960-12-25
著者
-
粟津 荘司
Faculty of Pharmaceutical Sciences, University of Tokyo
-
野上 寿
Faculty of Pharmaceutical Sciences, University of Tokyo
-
渡辺 敬一
Faculty Of Pharmaceutical Sciences University Of Tokyo
-
野上 寿
Faculty Of Pharmaceutical Sciences University Of Tokyo
-
佐藤 和彦
Faculty of Pharmaceutical Sciences, University of Tokyo
-
佐藤 和彦
Faculty Of Pharmaceutical Sciences University Of Tokyo
関連論文
- Studies on Ligand Binding Properties of Z-Fraction from Rat Liver Cytosol using 1-Anilino-8-Naphthalenesulfonate
- Pharmacokinetic Studies of Biliary Excretion. V. The Relationship between the Biliary Excretion Behavior and the Elimination from Plasma of Xanthene Dyes and Bromsulphthalein in Rat
- Pharmacokinetic Studies of Biliary Excretion. IV. The Relationship between the Biliary Excretion Behavior and the Elimination from Plasma of Azo Dyes and Triphenylmethane Dyes in Rat
- Pharmacokinetic Study of Biliary Excretion. III. Comparison of Excretion Behavior in Xanthene Dyes, Fluorescein and Bromsulphthalein
- Pharmacokinetic Study of Biliary Excretion. II. Comparison of Excretion Behavior in Triphenylmethane Dyes
- Pharmacokinetic Studies of Biliary Excretion. I. Comparison of the Excretion Behavior in Azo Dyes and Indigo Carmine
- Pharmacokinetic Aspects of Biliary Excretion. Dose Dependency of Riboflavin in Rat
- Studies on Tablet Disintegration. I. The Effect of Penetrating Rate on Tablet Disintegration.
- Generalized Consideration of Administration Route Dependence of Drug Disposition and Use of Urinary Data for Prediction of the Dependence
- Biliary Excretion Behavior Difference of Quaternary Ammonium Compounds between Portal Vein and Femoral Vein Infusion in Rat
- Studies on Powdered Preparations. XIX. Dissolution Kinetics of Benzoic Acid Derivatives
- Studies on Absorption and Excretion of Drugs. V. On the Mechanism of Penetration of Sulfisomezole through the Intestinal Barrier in vitro
- Studies on Absorption and Excretion of Drugs. III. Kinetics of Penetration of Sulfonamides through the Intestinal Barrier in Vitro.
- Adsorption of Benzoic Acid Derivatives by Carbon Black from Aqueous Solution and Related Phenomena
- Adsorption of Local Anesthetics from Aqueous Solution. Analysis of Factors Affecting the Nerve Blocking
- Model Barrier Affecting Drug Transport
- Dissolution Kinetics of Barbital Polymorphs
- Dissolution Kinetics of Polyvinylpyrrolidone of Various Molecular Weights
- The Pharmacokinetic Study on the Fate of 8-Hydroxyquinoline in Rat
- Kinetic Studies on Decomposition of Glutathione. III. Peptide Bond Cleavage and Desulfurization in Aqueous Solution
- Kinetic Studies on Decomposition of Glutathione. II. Anaerobic Decomposition in Aqueous Solution
- Studies on Absorption and Excretion of Drugs. VI. Effects of Cations and 2,4-Dinitrophenol on the Transport of Sulfonamides through the Small Intestine of Rat
- Studies on Decomposition and Stabilization of Drugs in Solution. XX. Hydrolysis of Acylcholine
- Studies on Decomposition and Stabilization of Drugs in Solution. XIX. Critical Micelle Concentration of Acylcholine
- Studies on Decomposition and Stabilization of Drugs in Solution. XV. Hydrolysis of Sodium Octyl, Myristyl, Cetyl, and Pentadecane-8-sulfates.
- Studies on Decomposition and Stabilization of Drugs in Solution. II. Chemical Kinetic Studies on Aqueous Solution of Methantheline Bromide.
- Adsorption of Phenothiazines from Aqueous Solution. Approach to Understanding of Membrane Action
- Thiamine Derivatives of Disulfide Type. IX. Exchange Reactions between Symmetrical Disulfide and L-Cysteine
- Complexes of Polyethylene Oxide with Guanidine Hydrochloride and with Phenobarbital. Preliminary Structural Studies by Differential Scanning Calorimetry, Polarized Infrared Spectroscopy and X-Ray Fiber Photography
- Pharmacokinetic Aspects of Elimination from Plasma and Distribution to Brain and Liver of Barbiturates in Rat
- Thiamine Derivatives of Disulfide Type. XIV. Kinetic Studies on the Reaction between Thiamine and Propyl Propane-Thiolsulfinate or -Thiolsulfonate
- Pharmacokinetics of Thiamine Derivatives. II. Elimination of Thiamine Derivatives from the Blood of Rat
- Pharmacokinetics of Thiamine Derivatives. I. Formation of Thiamine from Thiamine Propyl Disulfide by Erythrocytes of Rat
- Solubilization of dl-α-Tocopherol by Bile Salts, Polysorbate 80 and Egg Lecithin
- In Vivo and In Vitro Fates of 8-Hydroxyquinoline Derivatives in Rat
- Various Factors affecting Intestinal Absorption of Iodochlorhydroxyquin in Rat and Man
- Differences in Species of Iodochlorhydroxyquin Absorption, Metabolism, and Excretion
- Relationship between the Morphological Character of 5-Nitroacetyl-salicylic Acid Crystals and the Decomposition Rate in a Humid Environment
- Thiamine Derivatives of Disulfide Type. V. Kinetic Studies of the Reaction between Thiamine Propyl Disulfide or Homologes and L-Cysteine
- Thiamine Derivatives of Disulfide Type. IV. The Exchange Reaction between Thiamine Propyl Disulfide and L-Cysteine
- Physico-chemical Approach to Biopharmaceutical Phenomena. V. Relationship between the Adsorption by Carbon Black from Aqueous Solution and the Biopharmaceutical Data of Barbituric Acid Derivatives
- Physico-chemical Approach to Biopharmaceutical Phenomena. IV. Adsorption of Barbituric Acid Derivatives by Carbon Black from Aqueous Solution
- Studies on Powdered Preparations. XIV. Wetting of Powder Bed and Disintegration Time of Tablet
- Factors Affecting Dissolution Rate of Cellulose Acetate Phthalate in Aqueous Solution
- Thiamine Derivatives of Disulfide Type. III. Enzyme Systems in Rat Intestine contributed for Thiamine Formation from the Disulfide Type Derivatives
- Thiamine Derivatives of Disulfide Type. II. The Formation of Thiamine from the Disulfide Derivatives in Rat Intestine in Vitro
- Thiamine Derivatives of Disulfide Type. I. Formation of Thiamine from Thiamine Propyl Disulfide in Rat Intestine in Vitro
- Studies on Decomposition and Stabilization of Drugs in Solution. XVIII. The Hydrolysis of Phthalylsulfathiazole
- Thiamine Derivatives of Disulfide Type. XV. The Ring Opening-closing Reactions of 4-Methylthiazolium Salts
- Binding of 1-Anilino-8-naphthalenesulfonate to Polyvinylpyrrolidone, Poly-N-vinyl-2-oxazolidone, Poly-N-vinyl-5-methyl-2-oxazolidone and Polyethylene Glycol-20M in Aqueous Solution
- Thiamine Derivatives of Disulfide Type. XI. Oxidation of Dipropyl Disulfide with Hydrogen Peroxide and Properties of the Products
- Thiamine Derivatives of Disulfide Type. XIII. Kinetic Studies on the Degradation of Propyl Propanethiolsulfonate by Hydroxyl Ion
- Thiamine Derivatives of Disulfide Type. XII. Kinetic Studies on the Reaction between Propyl Propane-Thiolsulfinate or -Thiolsulfonate and Cysteine
- Mechanism of Adsorption of Phenols by Carbon Black from Aqueous Solution
- Molecular Sizes of Phenothiazines taken upon the Adsorption from Aqueous Solution and upon the Permeation through Cellulose Membrane
- Permeation of Phenothiazines through Cellulose Membrane
- Analysis of Solubility Properties of L-Tryptophan in Aqueous Solution based on the Effects of Third Component on Optical Rotatory Dispersion and on Adsorption by Carbon Black
- The Stabilization Mechanism of Acylcholinesters in Aqueous Solution by Sodium Lauryl Sulfate
- Studies on Absorption and Excretion of Drug. XIII. The Sorption of Surface Active Agents into the Intestinal Tissue of Rat and Their Effect on the Drug Absorption in Vitro
- Dissolution Phenomena of Organic Medicinals involving Simultaneous Phase Changes
- Decomposition of Acetylsalicylic Acid and Its Derivatives in Solid State
- Binding of 1-Anilinonaphthalene-8-sulfonate to Water Soluble Synthetic Polymers
- Studies on Decomposition and Stabilization of Drugs in Solution. VII. Stabilization of Methantheline Bromide in Aqueous Solution by Surface-active Agents.
- Studies on Powdered Preparations. XVIII. Dissolution Rate of Sulfadiazine in Various Aqueous Solutions.
- Studies on Powdered Preparations. XVII. Dissolution Rate of Sulfonamides by Rotating Disk Method
- Studies on Powdered Preparations. XVI. Aging of Dried Aluminum Hyodroxide Gel in Aqueous Ammonia
- Studies on Powdered Preparations. XV. Aging of Dried Aluminum Hydroxide Gel under Humidity and in Water
- Studies on Powdered Preparations. XIII. Reaction between Dried Aluminum Hydroxide Gel and Organic Acid
- Studies on Powdered Preparations. IX. Thermal Analysis of the Velocity of Reaction between Dried Aluminum Hydroxide Gel and Acid.
- Thiamine Derivatives of Disulfide Type. VII. Kinetics between Thiamine Tetrahydrofurfuryl Disulfide and L-Cysteine or Its Derivatives
- Thiamine Derivatives of Disulfide Type. VI. Kinetic Studies of the Thiol-Exchange Reaction between Thiamine Disulfide and L-Cysteine
- Studies on Powdered Preparations. XX. Disintegration of the Aspirin Tablets containing Starches as Disintegrating Agent
- Studies on Decomposition and Stabilization of Drugs in Solution. III. Chemical Kinetic Studies on Aqueous Solution of 2-Diethylaminoethyl Diphenylglycolate Methobromide
- Studies on Powdered Preparations. III. Studies on Disintegration of Basic Magnesium Carbonate Tablet.
- Studies on Powdered Preparations. II. Studies on Tablet Disintegration of Calcium Carbonate by Thermal Analysis.
- Studies on Absorption and Excretion of Drugs. II. Kinetics of Penetration of Basic Drug, Aminopyrine, through the Intestinal Barrier in vitro.
- Studies on Absorption and Excretion of Drugs. I. Kinetics of Penetration of Acidic Drug, Salicylic Acid, through the Intestinal Barrier in vitro.
- Studies on Decomposition and Stabilization of Drugs in Solution. IX Stabilization of Acetylsalicylic Acid in Aqueous Solution by Surface-active Agents.
- Pharmacokinetic Analysis on the Disappearance of Ethoxybenzamide from Plasma. Statistical Treatment of Data of Two Compartmental Model by a Digital Computer
- Studies on Absorption and Excretion of Drug. VIII. The Release Rate in vivo of Antipyretic and Analgesic Drugs from Commercial Sugar Coated Tablets.
- Studies on Absorption and Excretion of Drugs. IV. Absorption of Various Sulfonamides from the Rat Small Intestine by the Perfusion Method in vivo.
- Studies on Percutaneous Absorption. II. Effect of the Incorporated Substance.