Studies on Powdered Preparations. III. Studies on Disintegration of Basic Magnesium Carbonate Tablet.
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概要
- 論文の詳細を見る
Disintegration of a granule and the tablet of basic magnesium carbonate was investigated, apparent particle-size distribution was compared, and the effects of binder and disintegrator was studied by thermal analysis. The relation between testing method for disintegration by U.S.P. and J.P., and the change of surface area was discussed, and the following conclusions were drawn. 1) Judging from the change of surface area, the effect of compressional force was not notable in a tablet prepared with well-disintegrating granule. 2) The disintegration time of a tablet prepared by direct compression was very prolonged and this relation was clearly recognized by the evaluation of apparent particle-size distribution of a tablet.
- 公益社団法人日本薬学会の論文
- 1959-05-10
著者
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長谷川 淳
Faculty Of Pharmaceutical Sciences University Of Tokyo
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野上 寿
Faculty Of Pharmaceutical Sciences University Of Tokyo
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仲井 由宜
Faculty Of Pharmaceutical Sciences University Of Tokyo
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