Thiamine Derivatives of Disulfide Type. XI. Oxidation of Dipropyl Disulfide with Hydrogen Peroxide and Properties of the Products
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概要
- 論文の詳細を見る
Investigation was made on the oxidation of dipropyl disulfide with hydrogen peroxide in acetic acid, as a basis for kinetic studies in the synthesis of thiamine propyl disulfide (TPD). Separation and detection methods of the oxidation products by thin-layer chromatography were established. Among these products, thiolsulfinate (PrSSOPr), thiolsulfonate (PrSSO_2Pr), sulfinic acid and sulfonic acid were identified. The stability, solubility, IR and UV-spectrum of PrSSOPr and PrSSO_2Pr, which react with thiamine to produce TPD, were examined.
- 公益社団法人日本薬学会の論文
- 1971-12-25
著者
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長谷川 淳
Faculty Of Pharmaceutical Sciences University Of Tokyo
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野上 寿
Faculty of Pharmaceutical Sciences, University of Tokyo
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青木 勝夫
Technological Research Laboratories, Research and Development Division, Takeda Chemical Industries,
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野上 寿
Faculty Of Pharmaceutical Sciences University Of Tokyo
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青木 勝夫
Pharmacy Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
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青木 勝夫
Pharmacy Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.
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