Large-Scale Preparation of (R)-1,2-Propanediol through Baker's Yeast-Mediated Bioreduction
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概要
- 論文の詳細を見る
A procedure for the preparation of (R)-1,2-propanediol on a large scale by baker's yeast-mediated bioreduction of acetol using ethanol as an energy source in reported. The bioreduction, catalyzed by NADH-dependent oxidoreductase, was effectively performed using a bubble-column reactor with fed-batch operation. When the reactor with 10 l of medium was bubbled at an aeration rate of 3 l/min, the final reaction medium contained 4%(w/w) (R)-1,2-propanediol with >98% enantiomeric excess.
- 公益社団法人日本生物工学会の論文
- 1993-11-25
著者
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TAKEUCHI Yoshio
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
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MATSUNO RYUICHI
Department of Food Science and Technology, Faculty of Agriculture, Kyoto University
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Yoshii Hidefumi
Department Of Chemical And Biochemical Engineering Toyama National College Of Technology
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Yoshii Hidefumi
Department Of Biochemical Engineering Toyama National College Of Technology
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KOMTANI TADASHI
Department of Chemical and Biochemical Engineering, Toyama National College of Technology
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Komtani Tadashi
Department Of Chemical And Biochemical Engineering Toyama National College Of Technology
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Yoshii Hidefumi
Department Of Applied Biological Science Kagawa University
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Takeuchi Yoshio
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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Matsuno Ryuichi
Deparment Of Food Science And Technology Faculty Of Agriculture Kyoto University
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Takeuchi Yoshio
Faculty Of Pharmaceutical Sciences Toyama Medical & Pharmaceutical University
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