Cleavage Specificity of Coxsackievirus 3C Proteinase for Peptide Substrate
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概要
- 論文の詳細を見る
The substrate requirements of coxsackievirus 3C proteinase (3C^<pro>) were investigated on the C-terminal side of the scissile bond using C-terminal truncated peptides of the substrate peptide Ac-EALFQGPPV. Not only the Gln-Gly bond of Ac-EALFQG-NH_2 but also the C-terminal amide group of Ac-EALFQ-NH_2 was hydrolyzed by 3C^<pro>, suggesting that the essential residues for cleavage by coxsackievirus 3C^<pro> would exist within the N-terminal 5 residues.
- 社団法人日本農芸化学会の論文
- 1996-04-23
著者
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Komano T
Kyoto Univ. Kyoto Jpn
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Komano Tohru
Laboratory Of Biochemistry Department Of Agricultural Chemistry Kyoto University
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Komano Tohru
京都大学
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TAMURA Takashi
Central Research Laboratory, Maruishi Pharmaceutical Co., Ltd.
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Tamura T
Department Of Biofunctional Chemistry Graduate School Of Natural Science And Technology Okayama Univ
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MIYASHITA Kinji
Central Research Laboratories, Maruishi Pharmaceutical Co., Ltd.
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OKUNISHI Junji
Central Research Laboratories, Maruishi Pharmaceutical Co., Ltd.
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UTSUMI Ryutaro
Laboratory of Biochemistry, Department of Agricultural Chemistry, Kinki University
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SATOH Nobukatsu
Central Research Laboratories, Maruishi Pharmaceutical Co., Ltd.
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Okunishi Junji
Central Research Laboratories Maruishi Pharmaceutical Co. Ltd.
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Utsumi R
Department Of Bioscience And Biotechnology Graduate School Of Agriculture Kinki University
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Satoh Nobukatsu
Central Research Laboratories Maruishi Pharmaceutical Co. Ltd.
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Miyashita Kinji
Central Research Laboratories Maruishi Pharmaceutical Co. Ltd.
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Komano T
Laboratory Of Cellular Biochemistry Division Of Applied Life Sciences Graduate School Of Agriculture
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Tamura Takashi
Central Research Laboratories Maruishi Pharmaceutical Co. Ltd.
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Tamura Takashi
Central Research Laboratories Maruishi Pharmaceutical Co. Ltd
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