Suppression of Dioxin Mediated Aryl Hydrocarbon Receptor Transformation by Ethanolic Extracts of Propolis
スポンサーリンク
概要
- 論文の詳細を見る
Present study demonstrated that the ethanolic extracts of propolis containing higher concentrations of flavonoids suppressed 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced aryl hydrocarbon receptor transformation in a dose-dependent manner. The IC50 values of propolis group 3 and group 12 were 1.2 and 3.6 μg/ml, respectively, indicating that propolis showed stronger antagonistic effects as compared with vegetable extracts.
- 社団法人 日本農芸化学会の論文
- 2004-04-23
著者
-
Ashida H
Department Of Biofunctional Chemistry Faculty Of Agriculture Kobe University
-
Ashida Hitoshi
Research Center For Food Safety And Security Graduate School Of Agricultural Science Kobe University
-
Ashida Hitoshi
Department Of Agricultural Chemistry Kobe University
-
Ashida Hitoshi
Graduate School Of Science & Technology Division Of Life Science Kobe University
-
Nishiumi Shin
Division Of Applied Chemistry In Bioscience Department Of Agrobioscience Graduate School Of Agricult
-
Park Yong
State University Of Campinas College Of Food Engineering (unicamp)
-
Fukuda Itsuko
Research Center For Food Safety And Security Graduate School Of Agricultural Science Kobe University
-
Ashida Hitoshi
Department Of Life Science Graduate School Of Science And Technology Kobe University
-
Ashida Hitoshi
Department Of Agrobioscience Graduate School Of Agricultural Science Kobe University:research Center
-
Ashida Hitoshi
Res. Center For Food Safety And Security Graduate School Of Agricultural Sci. Kobe Univ.
-
Fukuda Itsuko
Res. Center For Food Safety And Security Graduate School Of Agricultural Sci. Kobe Univ. 1-1 Rokkoda
-
Fukuda Ituko
Research Center For Food Safety And Security Graduate School Of Agricultural Science Kobe University
-
FUKUDA Itsuko
Kobe University, Department of Biofunctional Chamistry, Faculty of Agriculture
-
ASHIDA Hitoshi
Kobe University, Department of Biofunctional Chamistry, Faculty of Agriculture
-
NISHIUMI Shin
Kobe University, Department of Biofunctional Chamistry, Faculty of Agriculture
-
GUZMAN Julio
State University of Campinas, College of Food Engineering (UNICAMP), Department of Food Science, Lab
-
SATO Helia
State University of Campinas, College of Food Engineering (UNICAMP), Department of Food Science, Lab
-
PASTORE Glaucia
State University of Campinas, College of Food Engineering (UNICAMP), Department of Food Science, Lab
-
Sato Helia
State University Of Campinas College Of Food Engineering (unicamp) Department Of Food Science Labora
-
Guzman Julio
State University Of Campinas College Of Food Engineering (unicamp) Department Of Food Science Labora
-
Pastore G
State University Of Campinas College Of Food Engineering (unicamp) Department Of Food Science Labora
-
Nishiumi Shin
Kobe Univ. Kobe Jpn
-
Park Yong
State University Of Campinas College Of Food Engineering (unicamp) Department Of Food Science Laboratory Of Food Biochemistry
関連論文
- Aryl hydrocarbon receptor-mediated induction of the cytosolic phospholipase A_2α gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse hepatoma Hepa-1c1c7 cells(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)
- Structure-activity relationships of anthraquinones on the suppression of DNA-binding activity of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin(BIOCHEMICAL ENGINEERING)
- Effects of Combined Administration of Quercetin, Rutin, and Extract of White Radish Sprout Rich in Kaempferol Glycosides on the Metabolism in Rats
- Tea Catechin Suppresses Adipocyte Differentiation Accompanied by Down-regulation of PPARγ2 and C/EBPα in 3T3-L1 Cells
- 3-Amino-1, 4-dimethyl-5H-pyrido[4, 3-b]indole Induces Apoptosis and Necrosis with Activation of Different Caspases in Rat Splenocytes
- Suppressive Effect of Polysaccharides from the Edible and Medicinal Mushrooms, Lentinus edodes and Agaricus blazei, on the Expression of Cytochrome P450s in Mice(Food & Nutrition Science)
- 3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) Is Incorporated into Rat Splenocytes, Thymocytes, and Hepatocytes Through Monoamine Transporters and Induces Apoptosis(Food & Nutrition Science)
- Subsequent Products After Antioxidant Actions of β-Carotene and α-Tocopherol Have No Salmonella Mutagenicity(Food & Nutrition Science)
- Evoking Cytochrome P450 1A Activity Interferes with Apoptosis Induced by 3-Amino-1,4-dimethyl-5H-pyrido [4,3-b]indole (Trp-P-1) in Rat Hepatocytes under the Ex Vivo System(Food & Nutrition Science)
- Dietary Antioxidants Fail in Protection against Oxidative Genetic Damage in In Vitro Evaluation
- Detection of Biomarkers for Apoptosis in Rat Liver after Perfusion with 3-Amino-1,4-dimethyl-5H-pyrido [4,3-b] indole (Trp-P-1)
- Cytochrome P4501A1-Inhibitory Action of Antimutagenic Anthraquinones in Medicinal Plants and the Structure-activity Relationship
- Tryptophan Pyrolysis Products, Trp-P-1 and Try-P-2 Induce Apoptosis in Primary Cultured Rat Hepatocytes
- Antimutagenicity of Flavones and Flavonols to Heterocyclic Amines by Specific and Strong Inhibition of the Cytochrome P450 1A Family
- Effects of Dietary Lipid Peroxidation Products on Hormonal Responses in Primary Cultured Hepatocytes of Rats
- Hepatic Phosphoglucomutase Activity as a Marker of Oxidative Stress Induced by Pro-oxidative Drugs
- Relationship between Hepatic Phosphoglucomutase Activity and Oxidative Stress Caused by Dietary Products of Lipid Peroxidation(Food & Nutrition)
- Determination of Lipid Peroxide Contents in Rat Liver by a New Coloration Test
- The Induction of Lipid Peroxidation in Rat Liver by Oral Intake of 9-Oxononanoic Acid Contained in Autoxidized Linoleic Acid
- Synergistic Effects of Food Colors on the Toxicity of 3-Amino-1, 4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) in Primary Cultured Rat Hepatocytes
- High-throughput evaluation of aryl hydrocarbon receptor-binding sites selected via chromatin immunoprecipitation-based screening in Hepa-1c1c7 cells stimulated with 2,3,7,8-tetrachlorodibenzo-p-dioxin
- Identification of a Functional 2-keto-myo-Inositol Dehydratase Gene of Sinorhizobium fredii USDA191 Required for myo-Inositol Utilization
- Functional myo-Inositol Catabolic Genes of Bacillus subtilis Natto Are Involved in Depletion of Pinitol in Natto (Fermented Soybean)
- Genetic Modification of Bacillus subtilis for Production of D-chiro-Inositol, an Investigational Drug Candidate for Treatment of Type 2 Diabetes and Polycystic Ovary Syndrome
- Evaluation of Intestinal Dioxin Permeability Using Human Caco-2 Cell Monolayers
- Discovery of Novel 2′,3′,4′-Trihydroxy-2-phenylacetophenone Derivatives as Anti-Gram-Positive Antibacterial Agents
- Effects of Peroxidation Products of Linoleic Acid on Tryptophan-nicotinamide Metabolism in Rats
- Effect of Lipid Peroxidation Products on the Catabolic Fate of Nicotinamide in Rats(Food & Nutrition)
- Anthocyans Fail to Suppress Transformation of Aryl Hydrocarbon Receptor Induced by Dioxin
- Suppression of Dioxin Mediated Aryl Hydrocarbon Receptor Transformation by Ethanolic Extracts of Propolis
- Suppression of Cytochrome P450 1A1 Expression Induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Mouse Hepatoma Hepa-1c1c7 Cells Treated with Serum of (−)-Epigallocatechin-3-gallate- and Green Tea Extract-Administered Rats
- Black Tea Theaflavins Suppress Dioxin-Induced Transformation of the Aryl Hydrocarbon Receptor
- Biochemical Characteristics of Osmophilic Yeasts Isolated from Pollens and Honey
- Investigation of Flavonoid Aglycones in Propolis Collected by Two Different Varieties of Bees in the Same Region
- Inhibition of P-Glycoprotein Enhances the Suppressive Effect of Kaempferol on Transformation of the Aryl Hydrocarbon Receptor
- D-Pinitol and myo-Inositol Stimulate Translocation of Glucose Transporter 4 in Skeletal Muscle of C57BL/6 Mice
- Identification of Two Major Ammonia-Releasing Reactions Involved in Secondary Natto Fermentation
- Rapid Preparation of a Plasma Membrane Fraction from Adipocytes and Muscle Cells : Application to Detection of Translocated Glucose Transporter 4 on the Plasma Membrane
- Differential Substrate Specificity of Two Inositol Transporters of Bacillus subtilis
- Suppression of Cytochrome P450 1A1 Expression Induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Mouse Hepatoma Hepa-1c1c7 Cells Treated with Serum of (-)-Epigallocatechin-3-gallate- and Green Tea Extract-Administered Rats
- Possible Evidence of Contamination by Catechins in Deconjugation Enzymes from Helix pomatia and Abalone entrails
- Comparison of the Effects of Orally Administered Linoleic Acid, and Its Hydroperoxides and Secondary Autoxidation Products on Hepatic Lipid Metabolism in Rats(Food & Nutrition)
- Decrease of the NADPH Level in Rat Liver on Oral Administration of Secondary Autoxidation Products of Linoleic Acid(Food & Nutrition)
- Preparation of Water and Ethanolic Extracts of Propolis and Evaluation of the Preparations
- Practical non-targeted gas chromatography/mass spectrometry-based metabolomics platform for metabolic phenotype analysis(BIOINFORMATICS)
- Concentration of Catechins and Caffeine in Black Tea Affects Suppression of Fat Accumulation and Hyperglycemia in High-fat Diet-fed Mice
- Possible Evidence of Contamination by Catechins in Deconjugation Enzymes from Helix pomatia and Abalone entrails
- Xenobiotic Tolerance of Primary Cultured Hepatocytes in Rats Fed a High-Fat or High-Protein Diet
- Diagnosis of gastroenterological diseases by metabolome analysis using gas chromatography-mass spectrometry
- Highly sensitive and rapid profiling method for carotenoids and their epoxidized products using supercritical fluid chromatography coupled with electrospray ionization-triple quadrupole mass spectrometry(METHODS)
- Identification of Biomarkers of Stent Restenosis With Serum Metabolomic Profiling Using Gas Chromatography/Mass Spectrometry
- New Structure Descriptor in the Structure-Activity Relationship Study on the Suppression of Aryl Hydrocarbon Receptor Transformation by Anthraquinones
- Evaluation Methods for Facilitative Glucose Transport in Cells and Their Applications
- Highly sensitive and rapid profiling method for carotenoids and their epoxidized products using supercritical fluid chromatography coupled with electrospray ionization-triple quadrupole mass spectrometry
- Metabolic Profiling of Oxidized Lipid-Derived Volatiles in Blood by Gas Chromatography/Mass Spectrometry with In-Tube Extraction
- Highly sensitive and selective analysis of widely targeted metabolomics using gas chromatography/triple-quadrupole mass spectrometry(METHODS)
- Preventive Effects of Black Soybean Seed Coat Polyphenols against DNA Damage in Salmonella typhimurium
- Cinnamtannin A2, a Tetrameric Procyanidin, Increases GLP-1 and Insulin Secretion in Mice