Suppression of Cytochrome P450 1A1 Expression Induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Mouse Hepatoma Hepa-1c1c7 Cells Treated with Serum of (−)-Epigallocatechin-3-gallate- and Green Tea Extract-Administered Rats
スポンサーリンク
概要
- 論文の詳細を見る
The suppression of cytochrome P450 1A1 (CYP1A1) expression was examined in mouse hepatoma Hepa-1c1c7 cells treated with serum prepared from (−)-epigallocatechin-3-gallate- and green tea extract-administered rats. Catechins were found in the rat plasma after the administration. In Hepa-1c1c7 cells, 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 expression was suppressed by treatment with the rat serum. It is concluded that catechins can possibly modulate CYP1A1 expression.
著者
-
Tsutsui Miki
Division Of Natural Science Osaka Kyoiku University
-
Ashida Hitoshi
Research Center For Food Safety And Security Graduate School Of Agricultural Science Kobe University
-
SAKANE Iwao
Central Research Institute, Itoen Ltd.
-
Fukuda Itsuko
Research Center for Food Safety and Security, Graduate School of Agricultural Science, Kobe Universi
-
Fukuda Itsuko
Res. Center For Food Safety And Security Graduate School Of Agricultural Sci. Kobe Univ. 1-1 Rokkoda
-
Fukuda Ituko
Research Center For Food Safety And Security Graduate School Of Agricultural Science Kobe University
関連論文
- Aryl hydrocarbon receptor-mediated induction of the cytosolic phospholipase A_2α gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse hepatoma Hepa-1c1c7 cells(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)
- Structure-activity relationships of anthraquinones on the suppression of DNA-binding activity of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin(BIOCHEMICAL ENGINEERING)
- Suppressive Effect of Polysaccharides from the Edible and Medicinal Mushrooms, Lentinus edodes and Agaricus blazei, on the Expression of Cytochrome P450s in Mice(Food & Nutrition Science)
- Effects of Tea (Camellia sinensis) Chemical Compounds on Ethanol Metabolism in ICR Mice
- Hypoglycemic Effect of Extracts from Lagerstroemia speciosa L. Leaves in Genetically Diabetic KK-A^Y Mice
- High-throughput evaluation of aryl hydrocarbon receptor-binding sites selected via chromatin immunoprecipitation-based screening in Hepa-1c1c7 cells stimulated with 2,3,7,8-tetrachlorodibenzo-p-dioxin
- Identification of a Functional 2-keto-myo-Inositol Dehydratase Gene of Sinorhizobium fredii USDA191 Required for myo-Inositol Utilization
- Functional myo-Inositol Catabolic Genes of Bacillus subtilis Natto Are Involved in Depletion of Pinitol in Natto (Fermented Soybean)
- Genetic Modification of Bacillus subtilis for Production of D-chiro-Inositol, an Investigational Drug Candidate for Treatment of Type 2 Diabetes and Polycystic Ovary Syndrome
- Anthocyans Fail to Suppress Transformation of Aryl Hydrocarbon Receptor Induced by Dioxin
- Suppression of Dioxin Mediated Aryl Hydrocarbon Receptor Transformation by Ethanolic Extracts of Propolis
- Inhibition of Drug-Metabolizing Enzyme Activity in Human Hepatic Cytochrome P450s by Bisphenol A
- Effects of Plant Growth Regulators and Carbon Sources on Theanine Formation in Callus Cultures of Tea (Camellia sinensis)
- Suppression of Cytochrome P450 1A1 Expression Induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Mouse Hepatoma Hepa-1c1c7 Cells Treated with Serum of (−)-Epigallocatechin-3-gallate- and Green Tea Extract-Administered Rats
- Black Tea Theaflavins Suppress Dioxin-Induced Transformation of the Aryl Hydrocarbon Receptor
- Antioxidative Activity of Water Extracts of Lagerstroemia speciosa Leaves
- D-Pinitol and myo-Inositol Stimulate Translocation of Glucose Transporter 4 in Skeletal Muscle of C57BL/6 Mice
- Differential Substrate Specificity of Two Inositol Transporters of Bacillus subtilis
- Suppression of Cytochrome P450 1A1 Expression Induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Mouse Hepatoma Hepa-1c1c7 Cells Treated with Serum of (-)-Epigallocatechin-3-gallate- and Green Tea Extract-Administered Rats
- New Structure Descriptor in the Structure-Activity Relationship Study on the Suppression of Aryl Hydrocarbon Receptor Transformation by Anthraquinones