Genetic Modification of Bacillus subtilis for Production of D-chiro-Inositol, an Investigational Drug Candidate for Treatment of Type 2 Diabetes and Polycystic Ovary Syndrome
スポンサーリンク
概要
著者
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Ashida Hitoshi
Research Center For Food Safety And Security Graduate School Of Agricultural Science Kobe University
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Ashida Hitoshi
Department Of Agrobioscience Graduate School Of Agricultural Science Kobe University:research Center
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Yoshida Ken-ichi
Dep. Of Agrobioscience Graduate School Of Agricultural Sci. Kobe Univ.
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Kinehara Masaki
Department Of Agrobioscience Graduate School Of Agricultural Science Kobe University
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Morinaga Tetsuro
Department Of Agrobioscience Graduate School Of Agricultural Science Kobe University
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Yamaguchi Masanori
Central Research Laboratories Hokko Chemical Industry Co. Ltd.
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Yoshida Ken-ichi
Department Of Biofunctional Chemistry Faculty Of Agriculture Kobe University
関連論文
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- Structure-activity relationships of anthraquinones on the suppression of DNA-binding activity of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin(BIOCHEMICAL ENGINEERING)
- Effects of Combined Administration of Quercetin, Rutin, and Extract of White Radish Sprout Rich in Kaempferol Glycosides on the Metabolism in Rats
- Tea Catechin Suppresses Adipocyte Differentiation Accompanied by Down-regulation of PPARγ2 and C/EBPα in 3T3-L1 Cells
- 3-Amino-1, 4-dimethyl-5H-pyrido[4, 3-b]indole Induces Apoptosis and Necrosis with Activation of Different Caspases in Rat Splenocytes
- Suppressive Effect of Polysaccharides from the Edible and Medicinal Mushrooms, Lentinus edodes and Agaricus blazei, on the Expression of Cytochrome P450s in Mice(Food & Nutrition Science)
- 3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) Is Incorporated into Rat Splenocytes, Thymocytes, and Hepatocytes Through Monoamine Transporters and Induces Apoptosis(Food & Nutrition Science)
- Subsequent Products After Antioxidant Actions of β-Carotene and α-Tocopherol Have No Salmonella Mutagenicity(Food & Nutrition Science)
- Evoking Cytochrome P450 1A Activity Interferes with Apoptosis Induced by 3-Amino-1,4-dimethyl-5H-pyrido [4,3-b]indole (Trp-P-1) in Rat Hepatocytes under the Ex Vivo System(Food & Nutrition Science)
- Dietary Antioxidants Fail in Protection against Oxidative Genetic Damage in In Vitro Evaluation
- Detection of Biomarkers for Apoptosis in Rat Liver after Perfusion with 3-Amino-1,4-dimethyl-5H-pyrido [4,3-b] indole (Trp-P-1)
- Cytochrome P4501A1-Inhibitory Action of Antimutagenic Anthraquinones in Medicinal Plants and the Structure-activity Relationship
- Tryptophan Pyrolysis Products, Trp-P-1 and Try-P-2 Induce Apoptosis in Primary Cultured Rat Hepatocytes
- Antimutagenicity of Flavones and Flavonols to Heterocyclic Amines by Specific and Strong Inhibition of the Cytochrome P450 1A Family
- Effects of Dietary Lipid Peroxidation Products on Hormonal Responses in Primary Cultured Hepatocytes of Rats
- Hepatic Phosphoglucomutase Activity as a Marker of Oxidative Stress Induced by Pro-oxidative Drugs
- Relationship between Hepatic Phosphoglucomutase Activity and Oxidative Stress Caused by Dietary Products of Lipid Peroxidation(Food & Nutrition)
- Synergistic Effects of Food Colors on the Toxicity of 3-Amino-1, 4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) in Primary Cultured Rat Hepatocytes
- High-throughput evaluation of aryl hydrocarbon receptor-binding sites selected via chromatin immunoprecipitation-based screening in Hepa-1c1c7 cells stimulated with 2,3,7,8-tetrachlorodibenzo-p-dioxin
- Identification of a Functional 2-keto-myo-Inositol Dehydratase Gene of Sinorhizobium fredii USDA191 Required for myo-Inositol Utilization
- Functional myo-Inositol Catabolic Genes of Bacillus subtilis Natto Are Involved in Depletion of Pinitol in Natto (Fermented Soybean)
- Genetic Modification of Bacillus subtilis for Production of D-chiro-Inositol, an Investigational Drug Candidate for Treatment of Type 2 Diabetes and Polycystic Ovary Syndrome
- Bacillus subtilis LmrA Is a Repressor of the lmrAB and yxaGH Operons: Identification of Its Binding Site and Functional Analysis of lmrB and yxaGH
- Effects of Peroxidation Products of Linoleic Acid on Tryptophan-nicotinamide Metabolism in Rats
- Effect of Lipid Peroxidation Products on the Catabolic Fate of Nicotinamide in Rats(Food & Nutrition)
- Anthocyans Fail to Suppress Transformation of Aryl Hydrocarbon Receptor Induced by Dioxin
- Suppression of Dioxin Mediated Aryl Hydrocarbon Receptor Transformation by Ethanolic Extracts of Propolis
- Suppression of Cytochrome P450 1A1 Expression Induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Mouse Hepatoma Hepa-1c1c7 Cells Treated with Serum of (−)-Epigallocatechin-3-gallate- and Green Tea Extract-Administered Rats
- Black Tea Theaflavins Suppress Dioxin-Induced Transformation of the Aryl Hydrocarbon Receptor
- D-Pinitol and myo-Inositol Stimulate Translocation of Glucose Transporter 4 in Skeletal Muscle of C57BL/6 Mice
- Identification of Two Major Ammonia-Releasing Reactions Involved in Secondary Natto Fermentation
- Differential Substrate Specificity of Two Inositol Transporters of Bacillus subtilis
- Suppression of Cytochrome P450 1A1 Expression Induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Mouse Hepatoma Hepa-1c1c7 Cells Treated with Serum of (-)-Epigallocatechin-3-gallate- and Green Tea Extract-Administered Rats
- Comparison of the Effects of Orally Administered Linoleic Acid, and Its Hydroperoxides and Secondary Autoxidation Products on Hepatic Lipid Metabolism in Rats(Food & Nutrition)
- Decrease of the NADPH Level in Rat Liver on Oral Administration of Secondary Autoxidation Products of Linoleic Acid(Food & Nutrition)
- Efficient Whisker-mediated Gene Transformation in a Combination with Supersonic Treatment