Inhibitory Effects of Acylated Acyclic Sesquiterpene Oligoglycosides from the Pericarps of Sapindus rarak on Tumor Necrosis Factor-α-Induced Cytotoxicity

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概要

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• Four new acylated acyclic sesquiterpene oligoglycosides (1—4) were isolated from the pericarps of Sapindus rarak DC. together with four known acyclic sesquiterpene oligoglycosides, mukuroziosides Ia (5), Ib (6), IIa (7), and IIb (8). Their structures were elucidated on the basis of chemical and physicochemical evidence. These newly isolated compounds (1—4) were found to show inhibitory effects on tumor necrosis factor-α-induced cytotoxicity in L929 cells at concentrations of 30—100 μM.

• 公益社団法人　日本薬学会の論文

著者

• 森川 敏生

  Pharmaceutical Res. And Technol. Inst. Kinki Univ.

• Morikawa Toshio

  Pharmaceutical Research and Technology Institute, Kinki University

• Ninomiya Kiyofumi

  Pharmaceutical Research and Technology Institute, Kinki University

• Yuan Dan

  School of Traditional Chinese Medicine, Shenyang Pharmaceutical University

• Yoshikawa Masayuki

  Pharmaceutical Research and Technology Institute, Kinki University

• Muraoka Osamu

  Pharmaceutical Research and Technology Institute, Kinki University

• XIE Yuanyuan

  Pharmaceutical Research and Technology Institute, Kinki University

• OKAMOTO Masaki

  Pharmaceutical Research and Technology Institute, Kinki University

• Morikawa Toshio

  Pharmaceutical Research And Technology Institute Kinki University

• Okamoto Masaki

  Pharmaceutical Res. And Technol. Inst. Kinki Univ.

• Hayakawa Takao

  Pharmaceutical Research and Technology Institute, Kinki University

• Muraoka Osamu

  Pharmaceutical Res. And Technol. Inst. Kinki Univ.

• Morikawa T

  Research Institute Fuji Chemical Industries Ltd.

• Yuan Dan

  School Of Traditional Chinese Medicine Shenyang Pharmaceutical Univ.

• Hayakawa Takao

  Pharmaceutical Res. And Technol. Inst. Kinki Univ.

• Nakatani K

  Pharmaceutical Res. And Technol. Inst. Kinki Univ.

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