Antibacterial Activity of 5-Dialkylaminomethylhydantoins and Related Compounds
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概要
- 論文の詳細を見る
To find new antibacterial leads in the class of hydantoin derivatives, we carried out synthetic investigation and biological evaluation of the title hydantoin derivatives and related compounds. Among the hydantoin derivatives described in this article, compound 3o, in which a 2,6-dichlorophenyl ring was introduced at the N-3 position of the hydantoin nucleus, showed the highest levels of antibacterial activity against both Escherichia coli NBRC14237 (NIHJ) and Staphylococcus aureus ATCC6538P (gram-negative and gram-positive bacteria, respectively) strains.
- 公益社団法人 日本薬学会の論文
著者
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KASHIGE Nobuhiro
Faculty of Pharmaceutical Sciences, Fukuoka University
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Miake Fumio
Faculty Of Pharmaceutical Sciences Fukuoka University
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Sumoto Kunihiro
Faculty Of Pharmaceutical Sciences Fukuoka University
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Fujisaki Fumiko
Faculty Of Pharmaceutical Sciences Fukuoka University
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Shoji Kaori
Faculty of Pharmaceutical Science, Fukuoka University
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Shimodouzono Mari
Faculty of Pharmaceutical Science, Fukuoka University
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Kashige Nobuhiro
Faculty Of Pharmaceutical Sciences Fukuoka University
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Sumoto Kunihiro
Faculty of Pharmaceutical Science, Fukuoka University
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Miake Fumio
Faculty of Pharmaceutical Science, Fukuoka University
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Kashige Nobuhiro
Faculty of Pharmaceutical Science, Fukuoka University
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Fujisaki Fumiko
Faculty of Pharmaceutical Science, Fukuoka University
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