Preparation and Pharmacological Evaluation of 1-(1,4-Benzoquinon-2-yl)-1,2,3,4-tetrahydronaphthalenes as Potent Cerebral Protective Agents
スポンサーリンク
概要
- 論文の詳細を見る
Two new series of 1-(1,4-benzoquinon-2-yl)-1,2,3,4-tetrahydronaphthalenes (3,4) were synthesized for evaluation of their pharmacological activities. These compounds showed significant anti-lipid peroxidation (ALP) activities with rat brain homogenate and some of them possessed a protective effect against hypobaric hypoxia in mice.
- 公益社団法人日本薬学会の論文
- 1996-01-15
著者
-
Suzuki Kazutoshi
放射線医学総合研究所分子イメージング研究センター
-
Suzuki K
Pharmaceutical Frontier Research Laboratories Japan Tobacco Inc.
-
Suzuki Kenji
Suntory Institute For Biomedical Research Wakayamadai
-
SUMOTO Kunihiro
Faculty of Pharmaceutical Sciences, Fukuoka University
-
Satoh F
Suntory Institute For Biomedical Research Wakayamadai
-
Satoh Fumio
Soka University
-
Suzuki Kazutoshi
Department Of Medical Imaging National Institute Of Radiological Sciences
-
Suzuki Kazutoshi
Clinical Neuroimaging Section Department Of Molecular Neuroimaging Molecular Imaging Center National
-
Ishihara Takafumi
Suntory Institute For Biomedical Research Wakayamadai
-
Suzuki K
Molecular Imaging Center National Institute Of Radiological Sciences
-
Aisaka K
Biofrontier Laboratories Kyowa Hakko Kogyo Co. Ltd.
-
Aisaka K
Japan Tobacco Inc. Osaka Jpn
-
Aisaka Kazuo
Suntory Institute For Biomedical Research:cornell University Medical College
-
TATSUOKA TOSHIO
Suntory Institute for Biomedical Research
-
Tatsuoka T
Suntory Institute For Biomedical Research
-
MIYANO Sanae
Sagami Chemical Research Center
-
OGINO Ryoko
Suntory Institute for Biomedical Research, Wakayamadai
-
SATOH Fumio
Suntory Institute for Biomedical Research, Wakayamadai
-
MIYANO Seiji
Faculty of Pharmaceutical Sciences, Fukuoka University
-
KUROKI Manami
Suntory Institute for Biomedical Research
-
OHNO Tomochika
Suntory Institute for Biomedical Research
-
Sumoto Kunihiro
Faculty Of Pharmaceutical Sciences Fukuoka University
-
Ogino Ryoko
Suntory Institute For Biomedical Research Wakayamadai
-
Miyano S
Faculty Of Pharmaceutical Sciences Fukuoka University
-
Sumoto Kunihiro
Faculty of Pharmaceutical Science, Fukuoka University
-
AISAKA Kazuo
Suntory Institute for Biomedical Research
-
ISHIHARA Takafumi
Suntory Institute for Biomedical Research
関連論文
- CT-based 3D Dose-Volume Parameter of the Rectum and Late Rectal Complication in Patients with Cervical Cancer Treated with High-Dose-Rate Intracavitary Brachytherapy
- Stereoselective Introduction of Oxygen Functionalities at the 11β-Position of Erythrinan Skeleton : Total Syntheses of (±)-Erythristemine and (+)-Erythrartine
- Carbon Ion Radiotherapy : Clinical Experiences at National Institute of Radiological Science (NIRS)
- INHIBITION OF [^3H] GLUTAMATE RELEASE BY ZN^ IN RAT HIPPOCAMPAL SLICES
- Effect of Diphenylthiocarbazone (Dithizone) on Glutamate Level in Hippocampus Preparation in Vitro and in Vivo
- The Effects of Carbon Ion Irradiation Revealed by Excised Perforated Intestines as a Late Morbidity for Uterine Cancer Treatment
- Quantitative analysis of dopamine transporters in human brain using [^C]PE2I and positron emission tomography : evaluation of reference tissue models
- Synthesis of ^C-Labelled Bis (phenylalkyl) amines and Their in Vitro and in Vivo Binding Properties in Rodent and Monkey Brains (Medicinal Chemistry)
- Synthesis and Brain Regional Distribution of [^C]NPS 1506 in Mice and Rat: an N-Methyl-D-aspartate (NMDA) Receptor Antagonist(Medicinal Chemistry)
- A Prodrug of NMDA/Glycine Site Antagonist, L-703, 717, with Improved BBB Permeability : 4-Acetoxy Derivative and Its Positron-Emitter Labeled Analog
- Correlation between the Physicochemical Property of Some Nonsteroidal Anti-inflammatory Drugs and Changes in Adenosine Triphosphate, Glutathione and Hemoglobin in Rat Erythrocytes(Biopharmacy)
- DNA Strand Scission by D-Glucosamine and Its Phosphates in Plasmid pBR322(Biological Chemistry)
- Effects of Aspirin and/or Salicylate on Hydrolysis and Glucuronidation of Indomethacin in Rat Erythrocytes and Hepatocytes
- N-Long-chain Monoacylated Derivatives of 2,6-Diaminopyridine with Antiviral Activity
- Synthesis and Antiviral Activities of Some 4,4'- and 2,2'-Dihydroxytriphenylmethanes
- Synthesis and Antiviral Activities of Some 4,4'-Dihydroxytriphenylmethanes
- Synthesis of 2, 2'-Dihydroxybisphenols and Antiviral Activity of Some Bisphenol Derivatives
- Enzymatic Synthesis of Novel Disaccharides Using Disaccharide Phosphorylases
- Purification and Characterization of Trehalose Phosphorylase from Catellatospora ferruginea
- Properties of Maltose Phosphorylase from Propionibacterium freudenreichii
- Marked Production of Ginsenosides Rd, F_2, Rg_3, and Compound K by Enzymatic Method
- Enzymatic Preparation of Ginsenosides Rg_2, Rh_1, and F_1
- Synthesis and Antiviral Activities of N-Mono- and/or N,N'-Di- Carbamoyl and Acyl Derivatives of Symmetrical Diamines
- N-Monocarbamoyl Derivatives of Symmetrical Diamines with Antiviral Activity
- Synthesis and DNA Strand Breakage Activity of Some 1,4-Diazepines
- Clinical Results of Carbon Ion Radiotherapy at NIRS
- Two Regions Responsible for the Actin Binding of p57, a Mammalian Coronin Family Actin-Binding Protein
- The Role of Protein Kinase C in the Transient Association of p57, a Coronin Family Actin-Binding Protein, with Phagosomes
- Effects of smoking on the lung accumulation of [^C]McN5652
- Effect of ice algal community on the increase of chlorophyll a concentration during spring in coastal water of the Sea of Okhotsk
- STUDIES ON ANTITUMOR ACTIVITY OF QUASSINOIDS : SYNTHESIS AND ANTITUMOR ACTIVITY OF NOVEL AILANTHONE ANALOGUES
- Cloning and Sequencing of the Aldehyde Oxidase Gene from Methylobacillus sp. KY4400
- Production of Aldehyde Oxidases by Microorganisms and Their Enzymatic Properties
- Binding kinetics of ^C-N-methyl piperidyl benzilate (^C-NMPB) in a rhesus monkey brain using the cerebellum as a reference region
- Effects of anesthesia upon ^F-FDG uptake in rhesus monkey brains
- Ionic interaction of [^C]-N, α-dimethylbenzylamine (DMBA) in rodent brain
- Different sensitivities to competitive inhibition of benzodiazepine receptor binding of ^C iomazenil and ^C-flumazenil in rhesus monkey brain
- MR Imaging of Brain Injury Induced by Carbon Ion Radiotherapy for Head and Neck Tumors
- Introduction of autopsy imaging redefines the concept of autopsy : 37 cases of clinical experience
- Nucleotide Sequence of the FAD Synthetase Gene from Corynebacterium ammoniagenes and Its Expression in Escherichia coli
- Hyperexpression and Analysis of cho B Encoding Cholesterol Oxidase of Brevibacterium sterolicum in Escherichia coli and Streptomyces lividans
- On the Antibacterial Activity of Normal and Reversed Magainin 2 Analogs against Helicobacter pylori
- Studies on Antihypertensive Agents with Antithrombotic Activity.2.Syntheses and Pharmacological Evaluation of Pyrrolo[2,3-c]azepine Derivatives
- A Self-defense Gene Homologous to Tetracycline Effluxing Gene Essential for Antibiotic Production in Streptomyces aureofaciens
- Conserved Organization of Genes for Biosynthesis of Chlortetracycline in Streptomyces Strains
- Cloning and Nucleotide Sequence of the Gene Responsible for Chlorination of Tetracycline
- Synthesis and Pharmacological Evaluation of Pyrroloazepine Derivatives as Potent Antihypertensive Agents with Antiplatelet Aggregation Activity
- Renal Targeting of Arginine-Vasopressin by Modification with Carbohydrates at the Tyrosine Side Chain
- Synthesis and Antidiuretic Activities of Novel Glycoconjugates of Arginine-Vasopressin
- 2-Arylmethyl-1,4-benzoquinones. II. Novel Inhibitors of Platelet Aggregation : Synthesis and Pharmacological Evaluation
- 2-Arylmethyl-1,4-benzoquinones. I. Novel Inhibitors of Platelet Aggregation : Synthesis and Pharmacological Evaluation
- Preparation and Pharmacological Evaluation of 1-(1,4-Benzoquinon-2-yl)-1,2,3,4-tetrahydronaphthalenes as Potent Cerebral Protective Agents
- Synthesis of Reversed Magainin 2 Analogs Enhanced Antibacterial Activity
- Novel Malonamide Derivatives as α_vβ_3 Antagonists.Syntheses and Evaluation of 3-(3-Indolin-1-yl-3-oxopropanoyl)aminopropanoic Acids on Vitronectin Interaction with α_vβ_3
- A Conventional Route for the Synthesis of New Oxazolidin-2-one Derivatives with β-Aminoalanines
- Synthesis of N-[2-(1-Piperidinyl)ethyl]benzamides
- Synthesis of B-(sec-Amino)alanines
- Alpha-Human Atrial Natriuretic Peptide (α-hANP) Prevents Pulmonary Edema Induced by Arachidonic Acid Treatment in Isolated Perfused Lung from Guinea Pig
- Dose Volume Analysis of Radiotherapy for Inoperable Patients with Stage I–II Endometrial Carcinoma
- REGULATION OF VASCULAR RESISTANCE BY L-ARGININE-DERIVED NITRIC OXIDE
- REGULATION OF BLOOD PRESSURE BY L-ARGININE-DERIVED NITRIC OXIDE
- Preparation of 2,2'-Dihydroxytriphenylmethanes Using Metal Phenolates with Aromatic Aldehydes
- Preparation and Chemical Properties of 5-Dialkylaminomethylhydantoins and 2-Thio-Analogues
- Preferential Intramolecular Ring Closure of Aminoalcohols with Diethyl Carbonate to Oxazolidinones
- A Conventional New Procedure for N-Acylation of Unprotected Amino Acids
- Antibacterial Activity of 5-Dialkylaminomethylhydantoins and Related Compounds
- Dose Volume Analysis of Radiotherapy for Inoperable Patients with Stage I-II Endometrial Carcinoma
- Molecular Symmetry and Biological Activities of New Symmetrical Tris(2-aminoethyl)amine Derivatives
- The effects of piperidine and its related substances on blood vessels.
- Effect of the Angiotensin-converting Enzyme Inhibitor Alacepril on Ventricular Function and Beta-Adrenoceptor Number in Rabbits with Aortic Regurgitation.
- Effect of yohimbine on urethane-induced hyperglycemia in rats.