Mitochondrial ABC Transporter Atm1p Is Required for Protection against Oxidative Stress and Vacuolar Functions in Schizosaccharomyces pombe

スポンサーリンク

概要

• 論文の詳細を見る

• A potential correlation between mitochondrial and vacuolar functions is known to exit in yeast. Fission yeast atm1+, SPAC15A10.01, encodes a putative half-type ABC transporter with an N-terminal mitochondrial-targeting signal. In an attempt to evaluate the possible involvement of mitochondrion in vacuole function, a functional analysis of atm1+ was performed by gene disruption. Growth of the atm1 mutant was inhibited in the presence of oxidizing agents, and S. cerevisiae Atm1p was found to complement this growth defect. atm1Δ cells exhibited defects in fluid-phase endocytosis and vacuolar fusion under hypotonic stress. GFP-tagged Atm1p was observed to be localized in the mitochondria. These data strongly suggest that fission yeast Atm1p was not only involved in protection against oxidative stress, but also played a role in vacuolar functions.

• 社団法人 日本農芸化学会の論文
• 2005-11-23

著者

• Tanaka Naotaka

  Department of Life Science, Kagawa University

• TAKEGAWA Kaoru

  Department of Life Science, Faculty of Agriculture, Kagawa University

• Takegawa K

  Department Of Bioresource Science Faculty Of Agriculture Kagawa University

• Takegawa Kaoru

  Dep. Of Life Sciences Fac. Of Agriculture Kagawa Univ.

• Takegawa K

  Kagawa Univ. Kagawa Jpn

• Iwaki Tomoko

  Dep. Of Applied Bioresource Sci. Fac. Of Agriculture Ehime Univ.

• Iwaki Tomoko

  Department Of Biological Resources Faculty Of Agriculture Ehime University

• GIGA HAMA

  Research Center, Asahi Glass Co., Ltd.

• FUJITA Yasuko

  Department of Life Sciences, Faculty of Agriculture, Kagawa University

• Giga Hama

  Research Center Asahi Glass Co. Ltd.

• Takegawa K

  Dep. Of Life Sciences Fac. Of Agriculture Kagawa Univ.

• Takegawa Kaoru

  Department Of Applied Biological Science Faculty Of Agriculture Kagawa University:department Of Bios

• Takegawa K.

  Department Of Bioresource Science Faculty Of Agriculture Kagawa University

• Fujita Yasuko

  Health Technology Research Center National Institute Of Advanced Industrial Science And Technology (

• Fujita Yasuko

  Department Of Life Sciences Faculty Of Agriculture Kagawa University

• Tanaka Naotaka

  Department Of Bioresource Science Faculty Of Agriculture Kagawa University

• IWAKI Tomoko

  Department of Applied Bioresource Science, Faculty of Agriculture, Ehime University

関連論文

• Ethanol-tolerant Saccharomyces cerevisiae strains isolated under selective conditions by over-expression of a proofreading-deficient DNA polymerase δ(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
• Identification of a Sed5-like SNARE Gene LjSYP32-1 that Contributes to Nodule Tissue Formation of Lotus japonicus
• Atg22p, a Vacuolar Membrane Protein Involved in the Amino Acid Compartmentalization of Schizosaccharomyces pombe
• Vba2p, A Vacuolar Membrane Protein Involved in Basic Amino Acid Transport in Schizosaccharomyces pombe
• An α-Amylase Homologue, aah3, Encodes a GPI-Anchored Membrane Protein Required for Cell Wall Integrity and Morphogenesis in Schizosaccharomyces pombe
• Mitochondrial ABC Transporter Atm1p Is Required for Protection against Oxidative Stress and Vacuolar Functions in Schizosaccharomyces pombe
• Vesicle-mediated Protein Transport Pathways to the Vacuole in Schizosaccharomyces pombe
• Production and Characterization of Extracellular Uronic Acid-Containing Glycoproteins from Fusarium oxysporum
• Isolation and Characterization of a Glycosylation Mutant from Schizosaccharomyces pombe
• Degradation of β1→6 Galactofuranoside Linkages in the Polysaccharide of Fusarium sp. M7-1 by Endo-β-galactofuranosidase from Bacillus sp.
• Isolation and Identification of a Choline-linked Mannobiose in the Glycoproteins of Fusarium sp. M7-1
• Isolation and Characterization of a Novel Endo-β-galactofuranosidase from Bacillus sp.
• Isolation and Identification of Novel Acidic Oligosaccharides Derived from Glycoproteinsof Fusarium sp. M7-1
• Preparation of β(1→6)-Linked Galactofuranoside Oligomers from the Acidic Polysaccharide of Fusarium sp. M7-1
• Degradation of Unsaturated Polysaccharide Derived from Acidic Polysaccharide of Fusarium sp. : M7-1 by a Bacterium Isolated from Soil
• Deglycosylated Glucoamylase from Rhizopus niveus is Precipitated by Flavobacterium sp. Endo-β-N-acetylglucosaminidase(Microbiology & Fermentation Industry)
• Effect of Yeast Extract on Endo-β-N-acetylglucosaminidase Production by a Flavobacterium sp.(Microbiology & Fermentation Industry)
• Vacuolar Amino Acid Transporter Avt5p Is Responsible for Lithium Uptake in Schizosaccharomyces pombe
• A Set of loxP Marker Cassettes for Cre-mediated Multiple Gene Disruption in Schizosaccharomyces pombe
• Characterization of the Na^+ -ATPase Gene(ZENAI)from the Salt-Tolerant Yeast Zygosaccharomyces rouxii
• New insights into galactose metabolism by Schizosaccharomyces pombe: isolation and characterization of a galactose-assimilating mutant
• Identification of the Catalytic Acid-Base Residue of Arthrobacter Endo-β-N-Acetylglucosaminidase by Chemical Rescue of an Inactive Mutant
• Characterization of Endo-β-N-acetylglucosaminidase from Alkaliphilic Bacillus halodurans C-125
• Identification of Amino Acid Residues Essential for the Substrate Specificity of Flavobacterium sp. Endo-β-N-acetylglucosaminidase(Biochemistry & Molecular Biology)
• Plate Assay for Endo-β-N-Acetylglucosaminidase Activity Using a Chromogenic Substrate Synthesized by Transglycosylation with Arthrobacter Endo-β-N-Acetylglucosaminidase
• Primary Structure of an O-Linked Sugar Chain Derived from Glucose Oxidase of Aspergillus niger(Biological Chemistry)
• The Release of Oligosaccharides from Glycoproteins by Endo-β-N-Acetylglucosaminidase of Flavobacterium sp.
• Elucidation of the Role of Sugar Chains in Glycosylated-enzymes Using Endo-β-N-acetylglu-cosaminidase from Flavo-bacterium sp.
• Loss of a GPI-Anchored Membrane Protein Aah3p Causes a Defect in Vacuolar Protein Sorting in Schizosaccharomyces pombe
• Purification and Characterization of a Novel Lyase from Cellulomonas sp. that Degrades Fusarium and Gibberella Acidic Polysaccharides(Microbiology & Fermentation Industry)
• Effect of Deglycosylation of Polymannose Chains on the Properties of Yeast External Invertase
• Identification of O-α-D-Glucopyranosyluronate-(1→2)-D-galactose Isolated from the Acidic Polysaccharide of Fusarium sp. M7-1(Microbiology & Fermentation Industry)
• Purification and Properties of a Low-Molecular-Weight α-Mannosidase from Cellulomonas sp.
• β-Eliminative Cleavage of the Acidic Polysaccharide of Fusarium sp. M7-1 by an Enzyme Preparation of Cellulomonas sp.(Microbiology & Fermentation Industry)
• Action of β-Mannosidases on O-β-D-Mannopyranosyl-(1→2)-D-mannose(Biological Chemistry)
• Synthesis of Bioactive Peptide Glycosylated at Two Sites
• Effects of Glycosylation on the Structure and the Biological Activiry of Peptides
• Chemo-Enzymatic Synthesis of a Calcitonin Derivative Containing a High-Mannose Type Oligosaccharide by Endo-β-N-Acetylglucosaminidase from Arthrobacter protophormiae
• Isolation of Suppressor Mutants of Phosphatidylinositol 3-Phosphate 5-kinase Deficient Cells in Schizosaccharomyces pombe(Microbiology & Fermentation Technology)
• Inportance of Phosphatidylinositol 3-Phosphate in Sporulation of Schizosaccharomyces pombe(Biochemistry & Molecular Biology)
• Functional Conservation between Fission Yeast moc1/sds23 and Its Two Orthologs, Budding Yeast SDS23 and SDS24, and Phenotypic Differences in Their Disruptants
• エンドグリコシダーゼの糖転移活性とその応用
• Enzymatic characteristics of a Ser/Thr protein kinase, SpkA, from Myxococcus xanthus(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
• 分裂酵毋 Schizosaccharomyces pombe におけるガラクトース鎖付加機構と生理的役割
• Site-independent Activity Enhancement of Calcitonin by N-Acetylglucosamine Attachment
• Infantile convulsions with mild gastroenteritis
• Activation of Endo-β-N-Acetylglucosaminidase from Arthrobacter protophormiae by Various Sugars
• New insights into galactose metabolism by Schizosaccharomyces pombe: Isolation and characterization of a galactose-assimilating mutant(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
• 糖鎖付加カルシトニンの立体構造と生理活性
• Upregulation of Genes Involved in Gluconeogenesis and the Glyoxylate Cycle Suppressed the Drug Sensitivity of an N-Glycan-Deficient Saccharomyces cerevisiae Mutant
• The och1 Mutant of Schizosaccharomyces pombe Produces Galactosylated Core Structures of N-Linked Oligosaccharides
• Transfer of High-Mannose-Type Oligosaccharides to Disaccharides by Endo-β-N-Acetylglucosaminidase from Arthrobacter protophormiae
• Purification and Properties of Chondroitinase Produced by a Bacterium Isolated from Soil
• PXA Domain-Containing Protein Pxa1 Is Required for Normal Vacuole Function and Morphology in Schizosaccharomyces pombe
• Loss of a GPI-Anchored Membrane Protein Aah3p Causes a Defect in Vacuolar Protein Sorting in Schizosaccharomyces pombe
• Vba2p, A Vacuolar Membrane Protein Involved in Basic Amino Acid Transport in Schizosaccharomyces pombe
• Galactinol Synthase Gene of Coptis japonica Is Involved in Berberine Tolerance
• Vacuolar Amino Acid Transporter Avt5p Is Responsible for Lithium Uptake in Schizosaccharomyces pombe
• Atg22p, a Vacuolar Membrane Protein Involved in the Amino Acid Compartmentalization of Schizosaccharomyces pombe
• Upregulation of Genes Involved in Gluconeogenesis and the Glyoxylate Cycle Suppressed the Drug Sensitivity of an N-Glycan-Deficient Saccharomyces cerevisiae Mutant
• A comprehensive HPLC analytical system for the identification and quantification of hexoses that employs 2-aminobenzamide coupling
• Nystatin Effects on Vacuolar Function in Saccharomyces cerevisiae
• Isolation and Identification of Ethyl-β-N-Acetylglucosaminide from Yeast Extract
• The Presence of Trehalose-containing Oligosaccharides in Yeast Extract
• Characterization of Two Genes Encoding Putative Cysteine Synthase Required for Cysteine Biosynthesis in Schizosaccharomyces pombe
• New insights into galactose metabolism by Schizosaccharomyces pombe : Isolation and characterization of a galactose-assimilating mutant
• Disruption of the plr1^+ Gene Encoding Pyridoxal Reductase of Schizosaccharomyces pombe
• Enrichment and Characterization of a Trichloroethene-Dechlorinating Consortium Containing Multiple "Dehalococcoides" Strains
• Schizosaccharomyces pombe Pep12p is required for vacuolar protein transport and vacuolar homotypic fusion(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)
• Galactose-Specific Recognition System in the Fission Yeast Schizosaccharomyces pombe
• CUE Domain-Containing Protein Vps901 Is Required for Vacuolar Protein Transport in Schizosaccharomyces pombe
• CUE Domain-Containing Protein Vps901 Is Required for Vacuolar Protein Transport in Schizosaccharomyces pombe
• 分裂酵母 Schizosaccharomyces pombe におけるガラクトース特異的な認識システム
• Functional Expression of Schizosaccharomyces pombe Vba2p in the Vacuolar Membrane of Saccharomyces cerevisiae
• Purification and Characterization of Endo-β-N-acetylglucosaminidase from a Flavobacterium sp.
• Effect of Protease Digestion on the Activity of Sugardepleted Enzymes Prepared with Endo-β-N-acetylglucosaminidase from Flavobacterium sp.

もっと見る 閉じる

スポンサーリンク