Vacuolar Amino Acid Transporter Avt5p Is Responsible for Lithium Uptake in Schizosaccharomyces pombe
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概要
- 論文の詳細を見る
The fission yeast Schizosaccharomyces pombe was sensitive to salinity; cell growth was stopped by 0.5 M NaCl and by 10 mM LiCl. The avt5+ gene encodes a vacuolar transporter with a broad specificity for amino acids. We found that the avt5Δ mutant became highly tolerant of Li+ and Na+ in growth. Concanamycin A-sensitive Li+ uptake as well as cellular Li+ content was lower in the avt5 mutant, suggesting a role of Avt5p in cellular uptake of toxic Li+.
- 社団法人 日本農芸化学会の論文
著者
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Iwaki Tomoko
Department Of Biological Resources Faculty Of Agriculture Ehime University
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SEKITO Takayuki
Department of Applied Bioresource Science, Faculty of Agriculture, Ehime University
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KAKINUMA Yoshimi
Department of Applied Bioresource Science, Faculty of Agriculture, Ehime University
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