Vacuolar Amino Acid Transporter Avt5p Is Responsible for Lithium Uptake in Schizosaccharomyces pombe

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概要

• 論文の詳細を見る

• The fission yeast Schizosaccharomyces pombe was sensitive to salinity; cell growth was stopped by 0.5 M NaCl and by 10 mM LiCl. The avt5+ gene encodes a vacuolar transporter with a broad specificity for amino acids. We found that the avt5Δ mutant became highly tolerant of Li+ and Na+ in growth. Concanamycin A-sensitive Li+ uptake as well as cellular Li+ content was lower in the avt5 mutant, suggesting a role of Avt5p in cellular uptake of toxic Li+.

• 社団法人 日本農芸化学会の論文
• 2010-08-23

著者

• Iwaki Tomoko

  Department Of Biological Resources Faculty Of Agriculture Ehime University

• SEKITO Takayuki

  Department of Applied Bioresource Science, Faculty of Agriculture, Ehime University

• KAKINUMA Yoshimi

  Department of Applied Bioresource Science, Faculty of Agriculture, Ehime University

• Iwaki Tomoko

  Faculty of Agriculture, Ehime University

• Sekito Takayuki

  Faculty of Agriculture, Ehime University

• Kakinuma Yoshimi

  Dep. Of Applied Bioresource Sci. Fac. Of Agriculture Ehime Univ.

• Kakinuma Yoshimi

  Faculty Of Agriculture Ehime University

• Sekito Takayuki

  Fac. Of Agriculture Ehime Univ.

• Inoue Tomohiro

  Faculty Of Agriculture Ehime University

• Kakinuma Y

  Integrated Center For Sciences (incs) Ehime University

• IWAKI Tomoko

  Department of Applied Bioresource Science, Faculty of Agriculture, Ehime University

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