Administration of Lysinoalanine-containing Proteins to Rats and the Characterization of Their Small Intestinal Contents
スポンサーリンク
概要
- 論文の詳細を見る
Gluten and casein, 100mg each, were dissolved in 4ml of0.2n NaOHand treated at 70°C for 1 hr. The amounts of lysinoalanine (LAL) formed were 4.0μmol in gluten and 12.8 μmol in casein. Each of the diets prepared with the LAL-containing proteins, i.e., LALgluten and LALcasein, was administered to rats by meal feeding. The rats of the LALgluten diet group and those of the LAL casein diet group were sacrificed at 4 hr and 2 hr, respectively, after the start of the meal feeding and their small intestinal contents investigated. LALgluten was found less digestible than the untreated gluten used as a control. A similar result was obtained whenLALcasein and untreated casein were compared for digestibility. Both in the LALgluten diet group and in the LAL casein diet group, the small intestinal LALwas located in a peptide fraction with a molecular weight of 1000-3000 daltons; no free LALwas detected in the small intestinal contents in either case. These results indicate that gluten and casein treated with alkali at a high temperature become resistant to efficient intralumen proteolysis, probably because of the high content of the LAL-involved crosslinkages which are formed.
- 社団法人 日本農芸化学会の論文
著者
-
Arai Soichi
Department Of Agricultural Chemistry Faculty Of Agriculture The University Of Tokyo
-
Abe Keiko
Department Of Agricultural Chemistry The University Of Tokyo
-
HOMMA Seiichi
Department of Bioscience, Tokyo University of Agriculture
-
FUJIMAKI Masao
Department of Agricultural Chemistry, University of Tokyo
-
HOMMA Seiichi
Department of Food and Nutrition, Ochanomizu University
-
ARAI Soichi
Department of Agricultural Chemicatry, The University of Tokyo
-
FUJIMAKI Masao
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo
関連論文
- Preparation of Hypoallergenic Wheat Flour Noodles and Evaluation of Their Physical Properties
- Vascular Ehlers-Danlos syndrome-All three coronary artery spontaneous dissections
- Nifedipine Interferes with Migration of Vascular Smooth Muscle Cells via Inhibition of Pyk2-Src Axis
- PE-127 Role of Src and Cas in Dorsal Ruffling, Lamellipodia and Migration in Vascular Smooth Muscle Cells(PE022,Atherosclerosis, Basic (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Angiotensin II-Induced Osteopontin Expression in Vascular Smooth Muscle Cells Involves G_, Ras, ERK, Src and Ets-1
- PJ-617 Role of HIF-1-dependent Expression of the VLDL Receptor in the Progression of Atherosclerosis(Atherosclerosis, basic(08)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Identification of β and γ Subunits of Laminins Localized in the Basement Membrane of Rat Circumvallate Papillae(Biochemistry & Molecular Biology)
- Changes in Cell Morphology and Cell-to-cell Adhesion Induced by Extracellular Ca^ in Cultured Taste Bud Cells(Biochemistry & Molecular Biology)
- PE-125 DNA Double-Strand Breaks and DNA Repair Enzyme Activity are Increased in Human Atherosclerotic Plaque(Atherosclerosis, basic-6, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OE-277 DEC1, a Member of the Fifth Clock-Gene Family, is Induced by Angiotensin II, Growth Factors, and Hypoxia in Vascular Cells(Hypertension, basic-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Addition of Signal Leader Sequences to the N-Termini of Olfactory Receptor Proteins Enhances Their Expression in Xenopus Oocyte
- Random Expression of Main and Vomeronasal Olfactory Receptor Genes in Immature and Mature Olfactory Epithelia of Fugu rubripes
- Identification of Taste-Tissue-Specific cDNA Clones from a Subtraction cDNA Library of Rat Circumvallate and Foliate Papiollae
- Molecular Cloning, Characterization, and Expression of Wheat Cystatins
- Salicylic Acid Carboxyl Methyltransferase Induced in Hairy Root Cultures of Atropa belladonna after Treatment with Exogeneously Added Salicylic Acid
- Importance of luxury flow for critically ill patients receiving a left ventricular assist system
- Structural Organization of the Gene Encoding Corn Cystatin
- Two Distinct Species of Corn Cystatin in Corn Kernels
- Organization and Primary Sequence of Multiple Genes Encoding Type II mRNA Species of Rice Prepro-glutelin(Biological Chemistry)
- A Mainstay of Functional Food Science in Japan-History, Present Status, and Future Outlook
- Invasive ductal adenocarcinoma of the pancreas may originate from the larger pancreatic duct : a study of 13 tumors less than 2cm in diameter
- Isolation and Characterization of a Novel Polysaccharide As a Possible Allergen Occurring in Wheat Flour
- Heterogeneous Nuclear Ribonucleoprotein K Interacts with and Is Proteolyzed by Calpain in vivo(Biochemistry & Molecular Biology)
- Purification and Characterization of an α-Amylase of Pichia burtonii Isolated from the Traditional Starter "Murcha" in Nepal
- Blood Substrates and Hormonal Responses to Increased Egg White Protein Intake Prior to a 12,000m Run in Heat
- Identification of Novel Fluorescent Pyrrolopyridinium Compound Formed from Maillard Reaction of 3-Deoxyglucosone and Butylamine
- Functional Expression and Enzymatic Properties of Two Sitophilus zeamais Cysteine Proteinases Showing Different Autolytic Processing Profiles In Vitro
- Purification and Properties of a Cysteine Proteinase Occurring in Dormant Wheat Seeds
- Characterization of a Gene Family Encoding Cysteine Proteinases of Sitophilus zeamais (Maize Weevil), and Analysis of the Protein Distribution in Various Tissues Including Alimentary Tract and Germ Cells
- Significance of the C-Terminal Domain of Erwinia uredovora Ice Nucleation-Active Protein(Ina U)
- Cloning and Sequencing of an Ice Nucleation Active Gene of Erwinia uredovora
- Large-scale Production and Purification of an Erwinia ananas Ice Nucleation Protein and Evaluation of Its Ice Nucleation Activity
- Establishment of Monoclonal Antibodies and Their Application to the Purification of Oryzacystatin(Biological Chemistry)
- Immunoassay of Oryzacystatin Occurring in Rice Seeds during Maturation and Germination(Biological Chemistry)
- Purification and Characterization of a Rice Cysteine Proteinase Inhibitor
- Peptide-bound Lysinoalanine Absorbed and Transported to the Kidney - Observation in a Feeding Test with Rats
- DPJ-010 Techinical and Theoretical Evaluation of Off-pump Surgical Radiofrequency Ablation(DPJ02,Cardiovascular Surgery/CABG (IHD),Digital Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Combined surgery for ischemic cardiomyopathy : Report of a case
- PJ-397 Impact of Radiofrequency Maze Surgery on Postoperative Cardiac Function(Arrhythmia, therapy(20)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- I-11 Slide-Styler(Pneumatic massage apparatus) increases blood pressure and decreases pulse rate in normal subjects.(Proceedings of the 45th Meeting of Japan Society of Physiological Anthropology)
- Papillary Muscle Head Approximation for the Treatment of Mitral Valve Regurgitation Combined With Aortic Valve Disease
- NMR Structural Studies of a Rice Cysteine Proteinase Inhibitor, Oryzacystatin-I
- Crystallization and Preliminary X-Ray Diffraction Studies of a Rice Cysteine Proteinase Inhibitor, Oryzacystation-I
- Surgical Treatments for Infective Endocarditis Involving Valve Annulus
- Exposure to a high total dosage of glucocorticoids produces non-alcoholic steatohepatits
- Primary Structure of an Allergenic Peptide Occurring in the Chymotryptic Hydrolysate of Gluten
- Fabrication and Quality Evaluation of Hypoallergenic Wheat Products
- Controlled Enzymatic Treatment of Wheat Proteins for Production of Hypoallergenic Flour
- Isolation and Cultivation of a Novel Ice Nucleation-active Strain of Xanthomonas campestris
- Freeze Concentration of Some Foodstuffs Using Ice Nucleation-active Bacterial Cells Entrapped in Calcium Alginate Gel(Food & Nutrition)
- Pulmonary Paragonimiasis Misdiagnosed as Tuberculosis : With Special References on Paragonimiasis
- Construction of a Bioreactor with Immobilized Yeast Cells for Production of a Low-phenylalanine Peptide Mixture as a Phenylketonuria Foodstuff(Food & Nutrition)
- Enlarged-scale Production of a Low-phenylalanine Peptide Substance as a Foodstuff for Patients with Phenylketonuria
- Transepithelial Transport of the Bioactive Tripeptide, Val-Pro-Pro, in Human Intestinal Caco-2 Cell Monolayers(Food & Nutrition Science)
- Chemical and Nutritional Properties of Hypoallergenic Wheat Flour
- Occurrence of Bound Salt in Freeze-concentrated Soy Sauce
- Inhibitory Effect of Arphamenine A on Intestinal Dipeptide Transport
- Physicochemical Study of Calcium-binding Properties of Chemical Substances as Inhibitors against Calcium Phosphate Insolubilization
- Inhibitory Activity of Oligo- and Poly-L-glutamic Acids against Calcium Phosphate Insolubilization and Calcium Binding with Special Relevance to Their Molecular Weight Dependence
- Gene Cloning and Characterization of a Bacillus vietnamensis Metalloprotease
- Gibberellin-responsive Gene Expression Taking Place with Oryzains α and γ as Cysteine Proteinases of Rice Seeds
- Nutritional Effects of an Oligopeptide Mixture with a Very High Fischer Ratio on the Amino Acid Absorption and Cerebral Amine Metabolism in Rats Suffering from Galactosamine-induced Liver Injurry(Food & Nutrition)
- Enzymatic Modification of Zein to Produce a Non-bitter Peptide Fraction with a Very High Fischer Ratio for Patients with Hepatic Encephalopathy(Food & Nutrition)
- High-Pressure Sterilization of Ice Nucleation-active Bacterial Cells(Food & Nutrition)
- Heat-induced Gel Properties of Freeze-concentrated Egg White Produced Using Bacterial Ice Nuclei(Food & Nutrition)
- n-Alkylphenyldimethylammonium Salts as Inhibitors of the Ice Nucleating Activity of Erwinia ananas(Food & Nutrition)
- Bioavailability of L-Methionine Oligomers in Rats(Food & Nutrition)
- Interaction of an Antinucleating Chemical and an Ice Nucleation Active Bacterium : a Case Study with an n-Octylbenzyldimethylammonium Salt and Erwinia ananas(Pesticide Chemistry)
- Alkylbenzyldimethylammonium Salts as Inhibitors for the Ice Nucleating Activity of Erwinia ananas(Pesticide Chemistry)
- No Immunotoxic Effect on T Cells with Di(2-Ethylhexyl)Phthalate in Male C57BL/6 Mice
- Modulating Effect of Sesamin, a Functional Lignan in Sesame Seeds, on the Transcription Levels of Lipid- and Alcohol-Metabolizing Enzymes in Rat Liver : A DNA Microarray Study
- Variance Analysis of a Clinical Pathway of Video-Assisted Single Lobectomy for Lung Cancer
- Blockade of Salmonella enteritidis Passage across the Basolateral Barriers of Human Intestinal Epithelial Cells by Specific Antibody
- Serum Cholesterol-Decreasing Effect of Heat-Moisture-Treated High-Amylose Cornstarch in Cholesterol-Loaded Rats
- pH-Dependent Structural Change in Neoculin with Special Reference to Its Taste-Modifying Activity
- Improvement of Digestibility, Reduction in Allergenicity, and Induction of Oral Tolerance of Wheat Gliadin by Deamidation
- Cell Culture and Motility Study on a Polymer Surface with a Nanometer-Scaled Stripe Structure
- Characterization and Regulation of Taurine Transport in Caco-2, Human Intestinal Cells
- Cathepsin D-Like Aspartic Proteinase Occurring in a Maize Weevil, Sitophilus zeamais, as a Candidate Digestive Enzyme
- Hypocholesterolemic Effect of Peanut Skin and Its Fractions : A Case Record of Rats Fed on a High-Cholesterol Diet
- Intraoperative Epicardial Echocardiography Locates the Origin of a Coronary-Pulmonary Artery Fistula
- Molecular Cloning and Characterization of an α-Amylase from Pichia burtonii 15-1
- Expression of the Stress-Related Genes for Glutathione S-Transferase and Ascorbate Peroxidase in the Most-Glycinin-Deficient Soybean Cultivar Tousan205 during Seed Maturation
- Application of an Aspergillus saitoi Protease Preparation to Soybean Curd to Modify Its Functional and Rheological Properties
- Antimicrobial Activity of Nutmeg against Escherichia coli O157
- Some Properties of a Cysteine Proteinase Inhibitor from Corn Endosperm(Biological Chemistry)
- Enzymatic Synthesis of [^N]-Methionine-incorporated Peptides by Papain(Food & Nutrition)
- Oryzacystatin Exogenously Introduced into Protoplasts and Regeneration of Transgenic Rice
- Gibberellin-induced Cysteine Proteinase Occurring in Germinating Rice Seeds and Its Specificity for Digesting Oxidized Insulin B-Chain(Food & Nutrition)
- Safety Evaluation of Hypoallergenic Wheat Flour by Using a DNA Microarray
- Freezing of Water in the Presence of the Ice Nucleation Active Bacterium, Erwinia ananas, and Its Application for Efficient Freeze-drying of Foods(Food & Nutrition)
- Studies on Functional Foods in Japan : State of the Art
- Effects of Peanut-Skin Procyanidin A1 on Degranulation of RBL-2H3 Cells
- Novel Angiotensin I-Converting Enzyme Inhibitory Peptides Found in a Thermolysin-Treated Elastin with Antihypertensive Activity
- Serum Cholesterol Reduction by Feeding a High-Cholesterol Diet Containing a Lower-Molecular-Weight Polyphenol Fraction from Peanut Skin
- Novel Angiotensin I-Converting Enzyme Inhibitory Peptides Found in a Thermolysin-Treated Elastin with Antihypertensive Activity
- Electrophoretical Analysis of Zein and Isolation of Its Components
- Enzymatic Modification of Protein Functionality: Implantation of Potent Amphiphilicity to Succinylated Proteins by Covalent Attachment of Leucine Alkyl Esters
- Administration of Lysinoalanine-containing Proteins to Rats and the Characterization of Their Small Intestinal Contents
- Incorporation of L-Leucine 1-13C-Dodecyl Ester to Succinylated αs1-Casein during a Papain-catalyzed Reaction