Studies on Palauan Medicinal Herbs. I. : Antidiabetic Effect of Ongael, Leaves of Phaleria cumingii (MEISN.) F. VILL.
スポンサーリンク
概要
- 論文の詳細を見る
A 50% ethanolic extract of Ongael [leaves of Phaleha cumingii (MEISN.) F. VILL.] showed remarkable blood glucose level decreasing effects on male KK-Ay mice and on sucrose loading test in male ddY mice. Meanwhile, the extract did not show blood glucose level decreasing effect on glucose loading test in male ddY mice. Activityguided fractionation of Ongael by using α-glucosidase inhibition assay led to the isolation ofa known xanthone C-glycoside, mangiferin, as an active constituent. HPLC analysis revealed that mangiferin contents in 50% ethanolic, methanolic and aqueous extracts of Ongael were 23.6%, 42.2% and 19.9%, respectively. On the basis of the mangiferin content of methanolic extract, Ongael contains a large amount (7.6%) of mangiferin.
- 日本生薬学会の論文
- 2004-12-20
著者
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HIRATA Noriko
School of Pharmacy, Kinki University
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角谷 真
京都薬科大学
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IWAHASHI Hiroyasu
School of Pharmaceutical Sciences, Kinki University
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Naruto S
School Of Pharmacy Kinki University
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Kubo M
School Of Pharmaceutical Sciences Kinki University
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Kubo Michinori
近畿大学 薬学部
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Tokunaga Masashi
A・pharma Kindai Co. Ltd
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Taniguchi M
Laboratory Of Pharmacognostical Sciences Osaka University Of Pharmaceutical Sciences
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Iwahashi Hiroyasu
School Of Pharmaceutical Sciences Kinki University
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Iwahashi Hiroyasu
近畿大学 薬学部薬用資源学研究室
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Hirata N
School Of Pharmacy Kinki University
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Hirata Noriko
Department Of Pharmaceutical Sciences Kinki University
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Tokunaga Masashi
近畿大学 薬学部
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Tokunaga Masashi
School Of Pharmaceutical Sciences Kinki University
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Kubo Michinori
Kyoto Pharmaceutical University
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Kubo Michinori
School Of Pharmaceutical Sciences Kinki University
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Naruto Shunsuke
School Of Pharmaceutical Sciences Kinki University
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TANIGUCHI Masahiko
Osaka University of Pharmaceutical Sciences
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Matsuda Hideaki
School Of Pharmacy Kinki University
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Hirata N
3rd Section Of Research And Development Toyo Suisan Kaisha Ltd.
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Hirata Noriko
School Of Pharmacy Kinki University
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Taniguchi Masahiko
Laboratory Of Pharmacognostical Sciences Osaka University Of Pharmaceutical Sciences
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Taniguchi Masahiko
Division Of Pharmacognosy Osaka University Of Pharmaceutical Sciences
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Kubo M
Kampo And Pharmacognosy Laboratory Tsumura And Co.
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Kubo M
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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Taniguchi M
Kyoto Res. Lab. Kyoto Jpn
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Iwahashi Hiroyasu
Kinki Univ. Osaka Jpn
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MATSUDA Hideaki
School of Pharmaceutical Sciences, Kinki University
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