A Novel Synthesis of 3-Aryl-5-tert-butyl-4-oxazolin -2-ones
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概要
- 論文の詳細を見る
An efficient synthetic method for 3-aryl-5-butyl-4-oxazolin-2-ones (6) is described. The reaction of ethyl N-arylcarbamates (10) with 1-bromo-3,3-dimethyl-2-butanone (9a) or 1-bromo-3-ethyl-3-methyl-2-pentanone (9b) using 2.2 eq of lithium bis(trimethylsilyl)amide afforded 6 in good yields. The reaction mechanisms are discussed.
- 公益社団法人日本薬学会の論文
- 1996-04-15
著者
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Sato K
Division Of Pharmacology National Institute Of Health Sciences
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TANIGUCHI Masahiko
Osaka University of Pharmaceutical Sciences
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Sato K
National Inst. Health Sci. Tokyo Jpn
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Taniguchi Masahiko
Division Of Pharmacognosy Osaka University Of Pharmaceutical Sciences
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SATO KAZUO
Agroscience Research Laboratories, Crop Protection Company, Sankyo Co. Ltd.
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KUDO Noriaki
Agroscience Research Laboratories, Sankyo Co., Ltd.,
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TANIGUCHI Misa
Agroscience Research Laboratories, Sankyo Co., Ltd.,
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Kudo N
Sankyo Co. Ltd. Shiga Jpn
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Kudo Noriaki
Agroscience Research Laboratories Sankyo Co. Ltd.
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Taniguchi M
Kyoto Res. Lab. Kyoto Jpn
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Sato K
Kyoritsu University Of Pharmacy
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Sato Kazuo
Agroscience Research Laboratories Sankyo Co. Ltd.
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