Michael-type Reaction of Ethyl Bromodifluoroacetate with α, β-Unsaturated Carbonyl Compounds in the Presence of Copper Powder

スポンサーリンク

概要

• 論文の詳細を見る

• We have reported that the reaction of ethyl bromodifluoroacetate (1) with alkenyl iodides in the presence of copper powder gives ethyl alkenyldifluoroacetates. As an extension of this reaction, reaction of 1 with Michael acceptors in the Presence of copper powder was examined and found to give 1,4-addition products selectively, unless the acceptor has a group stabilizing a radical intermediate, such as a phenyl group.

• 公益社団法人日本薬学会の論文
• 2000-07-01

著者

• 安藤 章

  Faculty of Pharmaceutical Sciences, Setsunan University

• Ando A

  Faculty Of Pharmaceutical Sciences Setsunan University

• Sato K

  National Inst. Health Sci. Tokyo Jpn

• OMOTE Masaaki

  Faculty of Pharmaceutical Sciences

• ANDO Akira

  Faculty of Pharmaceutical Sciences

• KUMADAKI Itsumaro

  Faculty of Pharmaceutical Sciences

• SATO Kazuyuki

  Faculty of Pharmaceutical Sciences, Setsunan University

• TAMURA Misato

  Faculty of Pharmaceutical Sciences, Setsunan University

• TAMOTO Kei

  Faculty of Pharmaceutical Sciences, Setsunan University

• Omote M

  Faculty Of Pharmaceutical Sciences Setsunan University

• Tamura Misato

  Faculty Of Pharmaceutical Sciences Setsunan University

• Kumadaki I

  Faculty Of Pharmaceutical Sciences Setsunan University

• Tamoto K

  Setsunan Univ. Osaka Jpn

関連論文

• Reactions of Trifluoromethyl Ketones. VIII. Investigation of Steric Effect of a Trifluoromethyl Group through Ene Reaction of Trifluoromethyl Ketones
• Studies on Trifluoromethyl Ketones. VII. Ene Reaction of Trifluoroacetaldehyde and Its Application for Synthesis of Trifluoromethyl Compounds
• THE STERIC EFFECT OF A TRIFLUOROMETHYL GROUP
• Synthesis of Fluorine Analogues of Protoporphyrin Potentially Useful for Diagnosis and Therapy of Tumors
• Reaction of Trifluoromethyl Ketones. VI. Synthesis of Trifluorinated Analogues of Monoterpenes
• Reaction of Trifluoromethyl Ketones. V. : Dehydration of Trifluoromethylated Homoallyl Alcohols : Synthesis of Trifluoromethylated Dienes
• Synthesis of Fluorine Analogues of Vitamin E. II. : Synthesis of 2-(3-Chloropropyl)-2,5,7,8-tetramethyl-6-chromanol and Its Application for Stereocontrolled Witting Reaction with Trifluoromethyl Ketones
• Synthesis of Fluorine Analogues of Vitamin E
• Advantage of the ESPRIT Method in Polarimetric Interferometry for Forest Analysis (Sensing)
• Polarimetric Characteristics of Forest at Coherent Decomposition in Polarimetric SAR Interferometry(Special Issue on New Technologies in Signal Processing for Electromagnetic-wave Sensing and Imaging)
• Glutathione Enhanced Anthraquinone Production in Adventitious Root Cultures of Rubia tinctorum L
• IDENTIFICATION OF MAJOR PIGMENTS CONTAINING D-AMINO ACID UNITS IN COMMERCIAL MONASCUS PIGMENTS
• Synthetic Studies of Psilocin Analogs Having Either a Formyl Group or Bromine Atom at the 5- or 7-Position^
• Synthesis of Fluorine Analogs of Vitamin E. IV. Synthesis of Bis(trifluoromethyl)tocopherols
• Synthesis of Formyl(2,2,2-trifluoro-1-hydroxyethyl)deuteroporphyrins and Their Derivatization to Porphyrin Derivatives with Elongated Side-Chains
• A Method for Synthesis of Fluorine Compounds Using Abnormal Grignard Reaction of Halothane. II. Reaction with Aldehydes and Unsaturated Ketones
• Synthesis of Fluorine Analogs of Vitamin E. III. Synthesis of 2-[4,8-Dimethyl-12-(trifluoromethyl)tridecyl]-2,5,7,8-tetramethyl-6-chromanol and 2-[4,12-Dimethyl-8-(trifluoromethyl)tridecyl]-2,5,7,8-tetramethyl-6-chromanol
• ENE REACTION OF N-TOSYLHEXAFLUOROACETONE IMINE
• 264 MHz HTS Lumped Element Bandpass Filter(Special Issue on Superconductive Devices and Systems)
• High-Temperature Superconducting Microstrip Line Filter for Mobile Telecommunication(Special Issue on Superconductive Electron Devices and Their Applications)
• Millimeter-Wave Microstrip Array Antenna for Automotive Radars(Antenna and Propagation)
• Millimeter-Wave Microstrip Line to Waveguide Transition Fabricated on a Single Layer Dielectric Substrate
• 1 Tbit/s (25 × 43 Gbit/s) Field Trial Using 43-Gbit/s/ch OTN Interface Prototype(Special Issue on 40 Gbit/s Optical Transmission Technologies)
• Dispersion Tolerant 80- Gbit /s Carrier-Suppressed Return-to-Zero (CS-RZ) Format Generated by Using Phase- and Duty-Controlled Optical Time Division Multiplexing (OTDM) Technique
• Carrier-Suppressed Return-to- Zero Pulse Generation Using Mode-Locked Lasers for 40-Gbit/s Transmission(Special Issue on 40 Gbit/s Optical Transmission Technologies)
• Millimeter-Wave Slotted Waveguide Array Antenna Manufactured by Metal Injection Molding for Automotive Radar Systems(Special Issue on Innovation in Antennas and Propagation for Expanding Radio Systems)
• Desing of High Slope-Efficiency Phase-Shifted DFB Laser Diodes with Asymmetrically-Pitch-Modulated(APM) Gratings(Special Issue on Advanced Optical Devices for Next Generation Photonic Networks)
• Robust IP Backbone Network Utilizing WDM Optical Paths (Joint Special Issue on Recent Progress in Optoelectronics and Communications)
• Flexible OADM Architecture and Its Impact on WDM Ring Evolution for Robust and Large-Scale Optical Transport Networks (Joint Special Issue on Recent Progress in Optoelectronics and Communications)
• Robust IP Backbone Network Utilizing WDM Optical Paths (Joint Special Issue on Recent Progress in Optoelectronics and Communications)
• Flexible OADM Architecture and Its Impact on WDM Ring Evolution for Robust and Large-Scale Optical Transport Networks (Joint Special Issue on Recent Progress in Optoelectronics and Communications)
• Synthesis of New Peptidic Glycoclusters Derived from β-Alanine Part 2 : Optionally Modulated Distance between Side-Chain Branched Points
• Synthetic Studies on Glycosphingolipids from Protostomia Phyla : Synthesis of Amphoteric Glycolipid Analogues Containing a Phosphocholine Residue from the Earthworm Pheretima hilgendorfi
• Synthesis and Herbicidal Activity of 1,5-Diarylpyrazole Derivatives
• A Novel Synthesis of 4H-1,4-Benzoxazines
• A Novel Synthesis of 3-Aryl-5-tert-butyl-4-oxazolin -2-ones
• Synthesis of 4,4-Difluoro-α-tocopherol Using a Cross-Coupling Reaction of Bromodifluoroacetate with Aryl Iodide in the Presence of Copper Powder
• Switching Device Based on RF-Field-Driven High-Tc SQUID(Special Issue on Superconductive Electronics)
• Josephson Switching Device Utilizing the Quantum Transitions in a Superconducting Quantum Interference Device Loop
• Synthesis of Fluorine Analogs of Protoporphyrin Potentially Useful for Diagnosis and Therapy of Cancer. IV.Synthesis of (Trifluorovinyl)vinyl-and (1-Chloro-2,2-difluorovinyl)vinyldeuteroporphyrins
• Synthesis of New Synthons for Organofluorine Compounds from Halothane Containing Sulfur Functional Groups
• Formation of Quaternary Carbon Center with a Trifluoromethyl Group Using a Pd-Catalyzed Allylation Reaction
• New Approach to a Novel Axially Chiral Ligand Showing Spontaneous Enrichment of Axial Chirality
• Michael-type Reaction of Ethyl Bromodifluoroacetate with α, β-Unsaturated Carbonyl Compounds in the Presence of Copper Powder
• Synthesis of Alkynyl- and Aryldifluoroacetate Using a Copper Complex from Ethyl Bromodifluoroacetate
• Synthesis of Organofluorine Compounds Using the Ene Reaction of N-(p-Toluenesulfonyl)trifluoroacetaldehyde Imine
• 4-Sulfenyl-2-carbamoyl-4-isoxazolin-3-ones : Biological Isostere to 4-Chloro-2-carbamoyl-4-isoxazolin-3-ones
• Reaction of Trifluoromethyl Ketones. IV. : Cyclization of the Ene Reaction Products of Trifluoromethyl Ketones : A Facile Synthesis of 2-(Trifluoromethyl)tetrahydrofuran(Organic,Chemical)
• A Method for Synthesis of Fluorine Compounds Using Abnormal Grignard Reaction of Halothane. III.Simple Synthesis of Trifluoromethylchloroolefins
• Asymmetric Reductive Aldol-Type Reaction with Carbonyl Compounds Using Dialkyl Tartrate as a Chiral Ligand

もっと見る 閉じる

スポンサーリンク