A Novel Synthesis of 4H-1,4-Benzoxazines

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概要

• 論文の詳細を見る

• The reaction of methyl 2-chloro-5-ethoxycarbonylamino-4-fluorobenzoate (4a) and 1-bromo-3,3-dimethyl-2-butanone (2) in the presence of 2.2 eq of lithium bis(trimethylsilyl)amide afforded the 4H-1,4-benzoxazine (6a) in good yield instead of the expected 4-oxazolin-2-one (5a). The generality of the reaction and the mechanism are discussed.

• 公益社団法人日本薬学会の論文
• 1996-09-15

著者

• Sato K

  Division Of Pharmacology National Institute Of Health Sciences

• Sato K

  National Inst. Health Sci. Tokyo Jpn

• FURUTA SATORU

  Agroscience Research Laboratories, Crop Protection Company, Sankyo Co. Ltd.

• SATO KAZUO

  Agroscience Research Laboratories, Crop Protection Company, Sankyo Co. Ltd.

• Furuta S

  Agroscience Research Laboratories Sankyo Co. Ltd.

• Furuta Satoru

  Agroscience Research Laboratories Crop Protection Company Sankyo Co. Ltd.

• KUDO Noriaki

  Agroscience Research Laboratories, Sankyo Co., Ltd.,

• Kudo N

  Sankyo Co. Ltd. Shiga Jpn

• Kudo Noriaki

  Agroscience Research Laboratories Sankyo Co. Ltd.

• Sato K

  Kyoritsu University Of Pharmacy

• Sato Kazuo

  Agroscience Research Laboratories Sankyo Co. Ltd.

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