Anti-inflammatory Activities of 70% Methanolic Extract from Cinnamomi Cortex
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概要
- 論文の詳細を見る
The effects of 70% methanolic extract (CC-ext) from Cinnamomi Cortex on acute and chronic inflammation were investigated.CC-ext inhibited the rise in vascular permeability induced by acetic acid and the increase of paw edema induced by carrageenin in mice. It was ineffective on edema derived by histamine or bradykinin, and exhibited only weak inhibitory effect on the edema derived by serotonin. CC-ext also showed inhibitory effects on the prekallikrein enzyme activity and ear edema induced by arachidonic acid. It also had an inhibitory effect on cotton pellet-induced granuloma but showed no atrophying action against the adrenal or thymus glands. Little effect was shown on secondary lesions in the development of adjuvant-induced arthritis (the arthritis reappeared from 11 to 27d after injection of the adjuvant). These results suggest that some active component having an inhibitory effect on acute inflammation is contained in Cinnamomi Cortex.
- 社団法人日本薬学会の論文
- 1996-08-15
著者
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角谷 真
京都薬科大学
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Matsuda Hideaki
Faculty of Pharmacy, Kinki University
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Kubo Michinori
近畿大学 薬学部
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KUBO Michinori
Faculty of Pharmaceutical Sciences, Kinki University
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WU Jianxin
Faculty of Pharmaceutical Sciences, Kinki University
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MA Shiping
Faculty of Pharmaceutical Sciences, Kinki University
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Wu Jianxin
Faculty Of Pharmaceutical Sciences Kinki University
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Ma Shiping
Faculty Of Pharmaceutical Sciences Kinki University
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Kubo Michinori
Faculty Of Pharmaceutical Sciences Kinki University
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Matsuda Hideaki
Faculty Of Pharmaceutical Sciences Kinki University
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Kubo M
Kampo And Pharmacognosy Laboratory Tsumura And Co.
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Kubo M
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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