Studies on Scutellariae Radix (VIII) : Anti-thrombic Actions of 70% Methanolic Extract and Various Fractions from Scutellariae Radix
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概要
- 論文の詳細を見る
A 70% methanol extract from Scutellariae Radix (root of Scutellaria baicalensis Georgi) inhibited the endotoxin-induced hepatic venous thrombosis in high butter diet-treated rats. EtOAc soluble fraction and insoluble fraction from the 70% methanol extract inhibited the endotoxin-induced decrease in blood platelets and fibrinogen, and the endotoxin-induced in- crease in fibrin degradation products (FDP) on disseminated intravascular coagulation in normal rats. In in vitro experiments, the EtOAc soluble fraction was shown to have inhibitory effect on collagen- and ADP-induced blood platelet aggregation, on thrombin-induced conversion of fibrinogen to fibrin and on the activity of plasminogen or plasmin.
- 日本生薬学会の論文
- 1984-12-20
著者
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Kubo Michinori
Faculty Of Pharmaceutical Sciences Kinki University
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Matsuda Hideaki
Faculty Of Pharmaceutical Sciences Kinki University
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