Anti-tumor Activity of Hot-water Extract of Hericium erinaceum (Bull.:Fr.) Pers. (Yamabushitake)
スポンサーリンク
概要
- 論文の詳細を見る
The anti-tumor activity of a lipophilic substance-free hot water extract (HE) of dried Hericium erinaceum was investigated. HE showed an inhibitory activity on the growth of intramuscularly transplanted sarcoma 180 ascitic cells: oral administration of HE at 500mg/kg and 250mg/kg gave inhibition rates of 51.8% and 47.2% of the control, and intraperitoneal administration of 1OOmg/kg and 50mg/kg, inhibition rates of 63.0% and 55.8%, respectively. HE did not inhibit the growth of HeLa 229 cells in Eagle's minimum essential medium (MEM). Therefore, the anti-tumor activity of HE is thought to be not due to its direct cytotoxic action on tumor cells.
- 日本生薬学会の論文
- 1999-10-20
著者
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Kubo Michinori
Faculty Of Pharmaceutical Sciences Kinki University
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Tani T
Toyama Medical And Pharmaceutical University
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Itoh Masaaki
Kyoritsu Pharmaceutical & Industrial Co. Ltd.
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Tani Tadato
Toyama Medical And Pharmaceutical University
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Nakata K
Dainippon Pharmaceutical Co. Ltd.
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MATSUIKE Yoshio
Kyoritsu Pharmaceutical & Industrial Co., Ltd.
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NAMBA Kensuke
Kyoritsu Pharmaceutical & Industrial Co., Ltd.
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NAKATA Katsuhisa
Dainippon Pharmaceutical Co., Ltd.
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Matsuike Yoshio
Kyoritsu Pharmaceutical & Industrial Co. Ltd.
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Namba Kensuke
Kyoritsu Pharmaceutical & Industrial Co. Ltd.
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