A Bioactive Polyphenolic Constituent in the Bark of Pterocarpus indicus, Willd and Its Effects on Animal Cell Phenotypes in Vitro(Biological Chemistry)
スポンサーリンク
概要
- 論文の詳細を見る
Earlier isolated plant polyphenol PI, which is carcinostatic on mice implanted with Ehrlich carcinoma [S. Takeuchi et al., Agric. Biol. Chem., 50, 569 (1986)], showed transient, nonspecific, non-cytotoxic growth inhibition in vitro on both normal and malignant cells. Examination of its effects on alteration of native and TPA-induced in vitro phenotypes revealed that PI suppress both the plasmin and ODC activities of the cells that increase with spontaneous malignancy, and also the TPA-induced ODC activity increase. TPA-induced decrease of ^<125>I-mEGF-binding ability was reversed by PI, to larger extent in the HeLa cells than in the untransformed RME-5-3-1 cells.
- 社団法人日本農芸化学会の論文
- 1986-05-23
著者
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KONO Yoshiki
The Institute of Physical and Chemical Research
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KONO Yoshiki
School of Agriculture, Ibaraki University
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Kono Y
Ibaraki Univ. Ibaraki Jpn
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SUZUKI Yoshikatsu
The Institute of Physical and Chemical Research (RIKEN)
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TAKEUCHI Setsuo
The Institute of Physical and Chemical Research
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NAMBATA Takeo
The Institute of Physical and Chemical Research
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TERADA Noriko
The Institute of Physical and Chemical Research
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WATANABE Ryoko
The Institute of Physical and Chemical Research
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KAWARADA Akira
The Institute of Physical and Chemical Research
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ADISEWOJO Sasongko
The Institute for Natural Sciences, Padjadjaran University
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Suzuki Y
Department Of Global Epidemiology Hokkaido University Research Center For Zoonosis Control
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Sugita-konishi Yoshiko
Department Of Veterinary Science Azabu University
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Suzuki Yoshihito
The Institute Of Enology And Viticulture Yamanashi University
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Suzuki Y
Research Institute For Bioresources Okayama University
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Sakai Y
Toyo Inst. Food Technology Jpn
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Terada N
The Institute Of Physical And Chemical Research
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Nambata T
The Institute Of Physical And Chemical Research
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Watanabe R
Niigata Women's Coll. Niigata Jpn
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Adisewojo Sasongko
The Institute For Natural Sciences Padjadjaran University
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Suzuki Y
Okayama Univ. Okayama Jpn
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SUZUKI Yoshikatsu
The Institute of Physical and Chemical Research
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