Studies on the Conformations of PM-Toxin, the Host-specific Corn Pathotoxin Produced by Phyllosticta maydis(Organic Chemistry)
スポンサーリンク
概要
- 論文の詳細を見る
To examine the conformation-toxicity relationship concerning PM-toxins, which are the fungus (Phyllosticta maydis)-produced host-specific corn pathotoxins having C_<33>- or C_<35>-linear poly-β-ketol structures, five mimics were synthesized as stereoisomeric mixtures in addition to twelve that had previously been synthesized. The synthetic mimic PM-B', which has a 1,3-diene spacer instead of the central saturated spacer in natural PM-toxin B, was 30- to 100-fold less toxic than the natural toxin, while PM-777B, C and D (which are isomers of PM-777A), and PM-77777 (which has six β-ketol groups) were as active as the natural toxin. These results suggest that the PM-toxins should take conformations (e.g., helix or hairpin forms) that are more involved than the previously considered simple ring-like forms.
- 社団法人日本農芸化学会の論文
- 1988-01-23
著者
-
KONO Yoshiki
The Institute of Physical and Chemical Research
-
Kondo H
Taisho Pharmaceutical Co.
-
KONO Yoshiki
School of Agriculture, Ibaraki University
-
Kono Y
Ibaraki Univ. Ibaraki Jpn
-
SUZUKI Yoshikatsu
The Institute of Physical and Chemical Research (RIKEN)
-
TAKEUCHI Setsuo
The Institute of Physical and Chemical Research
-
Suzuki Y
Department Of Global Epidemiology Hokkaido University Research Center For Zoonosis Control
-
Knoche H.
Department Of Biochemistry University Of Nebraska
-
Suzuki Y
Research Institute For Bioresources Okayama University
-
DALY J.
Department of Biochemistry, University of Nebraska
-
Daly J.
Department Of Biochemistry University Of Nebraska
-
DANKO S.
Department of Agricultural Biochemistry, University of Nebraska
-
Daly J.
Department Of Agricultural Biochemistry University Of Nebraska
-
Danko S.
Department Of Agricultural Biochemistry University Of Nebraska
-
SUZUKI Yoshikatsu
The Institute of Physical and Chemical Research
-
KNOCHE H.
Department of Agricultural Biochemistry, University of Nebraska
関連論文
- Isolation and Identification of (-)-Jasmonic Acid from Wild Rice, Oryza officinalis, as an Antifungal Substance(Organic Chemistry)
- Nordihydroguaiaretic Acid, of a New Family of Microtubule-stabilizing Agents, Shows Effects Differentiated from Paclitaxel(Biochemistry & Molecular Biology)
- Characterization of Glofibrate-induced Retrograde Golgi Membrane Movement to the Endoplasmic Reticulum : Clofibrate Distinguishes the Golgi from the Trans Golgi Network(Biochemistry & Molecular Biology)
- Glucosylceramide Synthesis Inhibitors Block Pharmacologically Induced Dispersal of the Golgi and Anterograde Membrane Flow from the Endoplasmic Reticulum : Implication of Sphingolipid Metabolism in Maintenance of the Golgi Architecture and Anterograde Mem
- Expression Pattern of the CsPK3 Auxin-Responsive Protein Kinase Gene
- CL-P1, a Newly Cloned Endothelial Cell Specific Scavenger Receptor
- Identification of a Peptide Mimic of Bioactive Gibberellins with Affinity to GA 2-Oxidase
- Sequential Regulation of Gibberellin, Brassinosteroid, and Jasmonic Acid Biosynthesis Occurs in Rice Coleoptiles to Control the Transcript Levels of Anti-Microbial Thionin Genes
- Haplotype analysis of the human collectin placenta 1 (hCL-P1) gene
- SNA-60-367 Components, New Peptide Enzyme Inhibitors of Aromatase : Structure of the Fatty Acid Side Chain and Amino Acid Sequence by Mass Spectrometry
- Propeptin, a New Inhibitor of Prolyl Endopeptidase Produced by Microbispora : II. Determination of Chemical Structure
- New Types of Liposidomycins Produced by Streptomyces that Inhibit Bacterial Peptidoglycan Synthesis Structure Elucidation of Fatty Acid Components by Tandem Mass Spectrometry
- Structural Analyses of Carbon Chains in 5-Alk(en)ylresorcinols of Rye and Wheat Whole Flour by Tandem Mass Spectrometry
- Structures of Oryzalides A and B, and Oryzalic Acid A, a Group of Novel Antimicrobial Diterpenes, Isolated from Healthy Leaves of a Bacterial Leaf Blight-resistant Cultivar of Rice Plant(Organic Chemistry)
- Identification of Three Clones Which Commonly Interact with the Kinase Domains of Highly Homologous Two Receptor-Like Kinases, RLK902 and RKL1
- Molecular Characterization of Two Highly Homologous Receptor-like Kinase Genes, RLK902 and RKL1, in Arabidopsis thaliana
- Nonselective Phytotoxins Simultaneously Produced with Host-selective ACTG-toxins by a Pathotype of Alternaria citri Causing Brown Spot Disease of Mandarins
- Studies on Host-selective Toxins Produced by a Pathotype of Alternaria citri Causing Brown Spot Disease of Mandarins(Organic Chemistry)
- A Bioactive Polyphenolic Constituent in the Bark of Pterocarpus indicus, Willd and Its Effects on Animal Cell Phenotypes in Vitro(Biological Chemistry)
- Identification and Characterization of a Novel Human Collectin CL-K1
- Molecular Cloning of Mouse Collectin Liver 1(Biochemistry & Molecular Biology)
- Effects of Partial Suppression of Ribosomal Protein S6 on Organ Formation in Arabidopsis thaliana(Biochemistry & Molecular Biology)
- Enzymatic Synthesis of Two Ginsenoside Re-β-xylosides
- Transglycosylation to Ginseng Saponins by Cyclomaltodextrin Glucanotransferases
- Identification of a Toxic Mechanism of the Plasticizers, Phtahlic Acid Esters, which are Putative Endocrine Disrupters : Time-dependent Increase in Quinolinic Acid and Its Metabolites in Rats Fed di (2-ethylhexyl) phthalate(Food & Nutrition Science)
- Elucidation of the Toxic Mechanism of the Plasticizers, Phthalic Acid Esters, Putative Endocrine Disrupters : Effects of Dietary Di(2-ethylhexyl)phthalate on the Metabolism of Tryptophan to Niacin in Rats(Food & Nutrition Science)
- Mepanipyrim, a Novel Inhibitor of Pharmacologically Induced Golgi Dispersion(Biochemistry & Molecular Biology)
- Marked Production of Ginsenosides Rd, F_2, Rg_3, and Compound K by Enzymatic Method
- Enzymatic Preparation of Ginsenosides Rg_2, Rh_1, and F_1
- Studies on a Quantitative Analysis of Oryzalides and Oryzalic Acids in Rice Plants by GC-SIM
- Structures of Oryzalic Acid B and Three Related Compounds, a Group of Novel Antibacterial Diterpenes, Isolated from Leaves of a Bacterial Leaf Blight-Resistent Cultivar of Rice
- Novel C_-Kaurane Type of Diterpene (Oryzalide A), a New Antimicrobial Compound Isolated from Healthy Leaves of a Bacterial Leaf Blight-resistant Cultivar of Rice Plant(Organic Chemistry)
- Structures of Two Novel Pyriculol-related Compounds and Identification of Naturally Produced Epipyriculol from Pyricularia oryzae(Organic Chemistry)
- Enzymatic Phosphatidylation of Thiamin, Pantothenic Acid, and Their Derivatives
- AtFLA11, a Fasciclin-Like Arabinogalactan-Protein, Specifically Localized in Screlenchyma Cells
- Effect of Lactational Exposure to Tributyltin Chloride on Innate Immunodefenses in the F1 Generation in Mice
- Preparation of Functional Single-Chain Antibodies against Bioactive Gibberellins by Utilizing Randomly Mutagenized Phage-Display Libraries
- Identification of Peptidyl Mimics of Bioactive Gibberellin Recognized by an Antibody
- Transglucosylation Activities of Multiple Forms of α-Glucosidase from Spinach(Biochemistry & Molecular Biology)
- SNF-4794: New Enzyme Inhibitors Produced by Chaetomella sp.
- Effect of Lactational Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin on the Susceptibility to Listeria Infection(Food & Nutrition Science)
- Expression of a Functional Single-chain Antibody against GA_ in Transgenic Tobacco
- Preparation and Application of Anti-idiotypic Antibody against Anti-gibberellin A_4 Antibody
- Specific Accumulation of Antifungal 5-Alk(en)ylresorchinol Homologs in Etiolated Rice Seedlings
- Structure of a New Antifungal C_-Hydroxyfatty Acid Isolated from Leaves of Wild Rice (Oryza officinalis)
- Toxic Activity of Mimics of the Host-Specific Pathotoxin PM-Toxin on Corn Carrying Texas Male-sterile Cytoplasm(Organic Chemistry)
- Subsite Affinities of α-Glucosidases from Spinach Seeds
- Molecular Cloning and Characterization of a cDNA Encoding Putative Phospholipid Hydroperoxide Glutathione Peroxidase from Spinach
- Multiple Molecular Forms of α-Glucosidase from Spinach Seeds, Spinacia oleracea L.
- Syntheses and Biological Activities of (±)-Streptovitacin A and E-73(Organic Chemistry)
- Synthesis and Biological Activities of Demethylcycloheximides(Organic Chemistry)
- Preparation of Chiral trans-2,4-Dimethyl-1-cyclohexanones, the Key Intermediates in Cycloheximide Synthesis, Using Microbial Resolution(Organic Chemistry)
- Absolute Structure of (-)-4,5-trans-Dihydroxy-3-methyl-2-cyclopentenone Isolated from the Marine Alga, Grateloupia filicina (Wulfen) J. Agardh by the Synthesis of Both Enantiomers(Organic Chemistry)
- Ankalactone, a New α,β-Unsaturated γ-Lactone from Monascus anka(Organic Chemistry)
- Two New Pyrogallols from the Marine Alga, Grateloupia filicina (Wulfen) J. Agardh(Organic Chemistry)
- Identification and Semi-Quantification of Glbberellms from the Pollen and Anthers of Zea mays by Immunoassay and GC/MS
- Metabolism and Translocation of Gibberellins in Seedlings of Pharbitis nil. : (I) Effect of Photoperiod on Stem Elongation and Endogenous Gibberellins in Cotyledons and Their Phloem Exudates : GROWTH AND DEVELOPMENT
- Studies on the Conformations of PM-Toxin, the Host-specific Corn Pathotoxin Produced by Phyllosticta maydis(Organic Chemistry)
- Characterization of Truncated Human Mannan-Binding Protein (MBP) Expressed in Escherichia coli
- Formation of β-Fructosyl Compounds of Pyridoxine in Growing Culture of Aspergillus niger
- Identification of Castasterone, Typhasterol and Teasterone from the Pollen of Zea mays(Organic Chemistry)
- Seasonal Changes of GA_1, GA_ and Abscisic Acid in Three Rice Cultivars
- Deoxyfunicone, a New γ-Pyrone Metabolite from a Resorcylide-producing Fungus (Penicillium sp.)(Organic Chemistry)
- Agrobacterium rhizogenes の保存温度とその期間が毛状根誘導能力に及ぼす影響
- Restriction Patterns of Plasmids Isolated from Ten Japanese Wild Strains of Agrobacterium rhizogenes
- Structure of HV-toxin M, a Host-specific Toxin-related Compound Produced by Helminthosporium victoriae(Organic Chemistry)
- Structure of HV-toxin M, a Host-specific Toxin-related Compound Produced by Helminthosporium victoriae
- Phospholipase D-Catalyzed Synthesis of Phosphatidyl Aromatic Compounds
- Enzymatic Synthesis of Novel Phosphatidylkojic Acid and Phosphatidylarbutin, and Their Inhibitory Effects on Tyrosinase Activity
- Comparison of Indole-3-acetic Acid Oxidation in Peroxidases from Rust-Infected Resistant Wheat Leaves
- Identification of Phenylglyoxal as a Flower-inducing Substance of Lemna from Pharbitis purpurea(Organic Chemistry)
- Biological Conversion of Benzoic Acid in Lemna paucicostata 151 and its Relation to Flower Induction
- Biosynthetic Study of Chloromonilicin, a Growth Self-inhibitor Having a Novel Lactone Ring, from Monilinia fructicola(Organic Chemistry)
- Chloromonilinic Acids A and B, Novel Catabolites of the Growth Self-inhibitor Chloromonilicin Isolated from Monilinia fructicola(Organic Chemistry)
- Structure of Amino Acids Isolated from Hydrolyzed HV-Toxin M, a Host-specific Toxin-related Compound Produced by Helminthosporium victoriae
- Relationship between Flower Induction by Benzoic Acid and its Metabolism in Lemna paucicostata 151
- Structure of the Major Component of ACRL-toxins, Host-specific Pathotoxic Compounds Produced by Alternaria citri
- Structure of the Host-selective Toxins Produced by a Pathotype of Alternaria citri Causing Brown Spot Disease of Mandarins
- Absolute Configuration of Oryzalexin A and Structures of Its Related Phytoalexins Isolated from Rice Blast Leaves Infected with Pyricularia oryzae
- A Bioactive Polyphenolic Constituent in the Bark of Pterocarpus indicus, Willd. I. Isolation and Characterization
- Synthesis and Biological Activity of a New Type of PM-Toxin Analogue Containing Oxygen Atoms in the Carbon-Chain Skeleton
- Novel Phytoalexins (Oryzalexins A, B and C) Isolated from Rice Blast Leaves Infected with Pyricularia oryzae. Part I: Isolation, Characterization and Biological Activities of Oryzalexins
- Isolation and Structure of a New Victoxinine Derivative Produced by Helminthosporium victoriae
- Synthesis of a Stereoisomeric Mixture of (±)-PM-Toxin B, a Host-specific Corn Pathotoxin Produced by Phyllosticta maydis